313229-95-7Relevant academic research and scientific papers
Catalytic asymmetric conjugate allylation of coumarins
Kuang, Yulong,Liu, Xiaohua,Chang, Lu,Wang, Min,Lin, Lili,Feng, Xiaoming
supporting information; experimental part, p. 3814 - 3817 (2011/09/15)
A catalytic asymmetric conjugate allylation was successfully developed to synthesize potential pharmacologically active 4-allyl-2-oxochroman skeletons. A dual activation strategy was employed by using N,N′-dioxide-Yb(OTf) 3 to activate coumarins and using (CuOTf)2?C 7H8 to activate tetraallyltin via transmetalation, respectively. Good yields and enantioselectivities were obtained under mild conditions.
Phosphine-catalyzed [3+2] cyclizations: Applications to the enantioselective synthesis of cyclopentene-fused chromanones and dihydroquinolinones
Neel, Mathilde,Gouin, Jerome,Voituriez, Arnaud,Marinetti, Angela
experimental part, p. 2003 - 2009 (2011/08/05)
Phosphine-promoted [3+2] cyclizations of allenic esters or phosphonates with coumarin derivatives were used to synthesize functionalized bicyclo[4.3.0]chroman-2-ones. Analogous bicyclo[4.3.0]quinolinones were similarly prepared by a two-step strategy invo
