313335-01-2

Basic information

• Product Name: Piperazine, 1-benzoyl-4-[(7-bromo-4-methoxy-1H-indol-3-yl)oxoacetyl]-
• CAS NO: 313335-01-2
• Molecular Formula: C22H20BrN3O4
• Molecular Weight: 470.322
• Mol File: 313335-01-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Piperazine, 1-benzoyl-4-[(7-bromo-4-methoxy-1H-indol-3-yl)oxoacetyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1-benzoyl-4-[(7-bromo-4-methoxy-1H-indol-3-yl)oxoacetyl]-(313335-01-2)
• EPA Substance Registry System: Piperazine, 1-benzoyl-4-[(7-bromo-4-methoxy-1H-indol-3-yl)oxoacetyl]-(313335-01-2)

Safety Data

• Hazardous Substances Data: 313335-01-2(Hazardous Substances Data)

Upstream product

• 81224-16-0 7-bromo-4-methoxy-1H-indole 
• 1293397-09-7 C₂₀H₂₄BrN₃O₅ 
• 1293397-10-0 C₁₅H₁₆BrN₃O₃ 
• 65-85-0 benzoic acid 

Downstream Products

• 1377584-54-7 C₂HF₃O₂*C₂₇H₂₆N₄O₅ 
• 1377584-52-5 C₃₂H₃₄N₄O₇ 
• 1293397-03-1 C₂₁H₁₈BrN₃O₄ 
• 1293397-04-2 C₃₃H₄₁BrN₆O₉ 
• 1293397-30-4 C₃₉H₄₅BrN₆O₁₃ 

Relevant articles and documents

TARGETED BIFUNCTIONAL DEGRADERS

The present invention provides, in one aspect, bifunctional compounds that can be used to promote or enhance degradation of certain circulating proteins. In another aspect, the present invention provides bifunctional compounds that can be used to promote or enhance degradation of certain autoantibodies. In certain embodiments, treatment or management of a disease and/or disorder requires degradation, removal, or reduction in concentration of the circulating protein or the autoantibody in the subject. Thus, in certain embodiments, administration of a compound of the invention to the subject removes or reduces the circulation concentration of the circulating protein or the autoantibody, thus treating, ameliorating, or preventing the disease and/or disorder. In certain embodiments, the circulating protein is TNF.