313353-93-4Relevant academic research and scientific papers
Catalytic Asymmetric Reduction of α-Trifluoromethylated Imines with Catecholborane by BINOL-Derived Boro-phosphates
He, Hualing,Tang, Xiaoxue,Cao, Yang,Antilla, Jon C.
, p. 4336 - 4345 (2021/03/01)
A catalytic enantioselective reduction of α-trifluoromethylated imines by a BINOL-derived boro-phosphate employing catecholborane as hydride source has been developed. This method provides an efficient route to prepare synthetically useful chiral α-triflu
Internally Reuse Waste: Catalytic Asymmetric One-Pot Strecker Reaction of Fluoroalkyl Ketones, Anilines and TMSCN by Sequential Catalysis
Liu, Yun-Lin,Yin, Xiao-Ping,Zhou, Jian
, p. 321 - 328 (2018/02/21)
We report a highly enantioselective one-pot facile synthesis of fluorinated Cα-tetrasubstituted amino nitriles from α-fluoroalkyl α-aryl ketones, anilines, and TMSCN through a sequential p-TsOH catalyzed ketimine formation and chiral bifunction
Chiral phosphoric acid catalyzed transfer hydrogenation: Facile synthetic access to highly optically active trifluoromethylated amines
Henseler, Alexander,Kato, Masanori,Mori, Keiji,Akiyama, Takahiko
supporting information; experimental part, p. 8180 - 8183 (2011/10/09)
Amines to an end: Highly optically active α-CF3- functionalized amines can be obtained using metal-free reaction conditions. The method involves the transfer hydrogenation of CF3-substituted ketimines catalyzed by 1 and reductive ami
