1313758-39-2Relevant academic research and scientific papers
N -Protecting group tuning of the enantioselectivity in Strecker reactions of trifluoromethyl ketimines to synthesize quaternary α-trifluoromethyl amino nitriles by ion pair catalysis
Du, Mengyuan,Yu, Longhui,Du, Ting,Li, Zhaokun,Luo, Yueyang,Meng, Xiangyu,Tian, Zhengtao,Zheng, Changwu,Cao, Weiguo,Zhao, Gang
supporting information, p. 1581 - 1584 (2020/02/13)
An enantioselective Strecker reaction to construct trifluoromethylated quaternary stereocenters with N-PMP and unexplored N-Boc trifluoromethyl ketimines catalyzed using an organophosphine dual-reagent catalyst has been developed. The enantioselectivities
Internally Reuse Waste: Catalytic Asymmetric One-Pot Strecker Reaction of Fluoroalkyl Ketones, Anilines and TMSCN by Sequential Catalysis
Liu, Yun-Lin,Yin, Xiao-Ping,Zhou, Jian
, p. 321 - 328 (2018/02/21)
We report a highly enantioselective one-pot facile synthesis of fluorinated Cα-tetrasubstituted amino nitriles from α-fluoroalkyl α-aryl ketones, anilines, and TMSCN through a sequential p-TsOH catalyzed ketimine formation and chiral bifunction
Organocatalytic asymmetric Strecker reaction of di- and trifluoromethyl ketoimines. Remarkable fluorine effect
Liu, Yun-Lin,Shi, Tao-Da,Zhou, Feng,Zhao, Xiao-Li,Wang, Xin,Zhou, Jian
supporting information; experimental part, p. 3826 - 3829 (2011/09/15)
A highly enantioselective Strecker reaction of difluoromethyl and trifluoromethyl ketoimines was developed. Remarkable fluorine effect on the reactivity and selectivity is observed and discussed.
