3134-35-8

Basic information

• Product Name: 5-chloro-2-(pyridin-3-yl)pyridine
• Synonyms: 5-chloro-2-(pyridin-3-yl)pyridine
• CAS NO: 3134-35-8
• Molecular Formula: C10H7ClN2
• Molecular Weight: 190.632
• Mol File: 3134-35-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 147-150 °C
• Boiling Point: 312.8±27.0 °C(Predicted)
• Density: 1.245±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 5-chloro-2-(pyridin-3-yl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-2-(pyridin-3-yl)pyridine(3134-35-8)
• EPA Substance Registry System: 5-chloro-2-(pyridin-3-yl)pyridine(3134-35-8)

Safety Data

• Hazardous Substances Data: 3134-35-8(Hazardous Substances Data)

Upstream product

• 626-55-1 3-Bromopyridine 
• 16110-09-1 2,5 dichloropyridine 
• 40473-01-6 2-Bromo-5-chloro-pyridine 
• 1120-90-7 3-iodopyridine 
• 1692-25-7 3-pyridylboronic acid 
• 329214-79-1 3-(4,4,5,5,-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 

Downstream Products

• 1201787-98-5 3-methoxy-6-pyrid-3-yl-9-(toluene-4-sulfonyl)-9H-pyrrolo[2,3-b:5,4-c']dipyridine 
• 1201787-99-6 3-methoxy-4-iodo-6-pyrid-3-yl-9-(toluene-4-sulfonyl)-9H-pyrrolo[2,3-b:5,4-c']dipyridine 
• 1201787-97-4 N-[4-(3-methoxy-6-(pyrid-3-yl)-9H-pyrrolo[2,3-b:5,4-c']dipyrid-4-yl)phenyl]methanesulfonamide 

Relevant articles and documents

Synthesis of Bis-heteroaryls Using Grignard Reagents and Pyridylsulfonium Salts

Herein are reported ligand-coupling reactions of Grignard reagents with pyridylsulfonium salts. The method has wide functional group tolerance and enables the formation of bis-heterocycle linkages, including 2,4′-, 2,3′-, and 2,2′-bipyridines, as well as pyridines linked to pyrimidines, pyrazines, isoxazoles, and benzothiophenes. The methodology was successfully applied to the synthesis of the natural products caerulomycin A and E.

AZACARBOLINE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME

The invention relates to novel azacarbonlines having formula (I), wherein: R3, R4 represent independently H; hal; CF3; substituted oxy, optionally substituted alkoxy; optionally substituted amino; substituted carbonyl; optionally substituted carboxyl; optionally substituted amide; sulphur, such as optionally substituted sulphones, sulphoxides or sulphides; linear, branched or cyclic C1-C10 alkyl optionally comprising an optionally substituted heteroatom; optionally substituted linear, branched or cyclic C2-C7 alkenyl; optionally substituted linear or branched C2-C6 alkynyl; optionally substituted aryl or heteroaryl; of which may be optionally substituted; in the form of a base or an acid addition salt. The invention also relates to the use of same in therapeutics for the treatment of cancer and to synthesis methods.