313405-40-2Relevant academic research and scientific papers
Synthesis and Antimicrobial Activity of Methyl 2-(2-(2-Arylquinazolin-4-yl)oxy) Acetylamino Alkanoates
Megahed,Fathalla,Alsheikh, Amer A.
, p. 2799 - 2808 (2018)
A series of methyl 2-(2-(2-arylquinazolin-4-yl)oxy) acetylamino alkanoate have been developed via N,N′-dicyclohexylcarbodiimide coupling of (2-arylquinazolin-4-yloxy) acetic acids with amino acid ester hydrochlorides. The O-substituted carboxylic acids we
Synthesis, antimicrobial evaluation, and docking studies of novel 4-substituted quinazoline derivatives as DNA-gyrase inhibitors
Boyapati, Shireesha,Kulandaivelu, Umasankar,Sangu, Srinivas,Vanga, Malla Reddy
experimental part, p. 570 - 576 (2011/06/24)
Quinazoline derivatives are reported to have anti-inflammatory, analgesic, antibacterial, and anticancer activities. The incorporation of "OCH 2CONH2" (oxymethylcarbamide) at 4th position of the quinazoline ring was found
Synthesis of new quinazoline derivatives of expected potential bioresponses
Isaac, Yvette A.,Arsanious, Mona H.,Abd El-Nabi, Hisham A.
, p. 1299 - 1307 (2007/10/03)
The reactivity of the novel compound ethyl (2-phenylquinazolin-4-oxy)-acetate (1), towards carbon electrophiles and nitrogen nucleophiles is described. Reaction of (2-phenylquinazolin-4-oxy)acetic hydrazine (5) with carbon electrophiles is also investigated. Futhermore, the behaviour of 4-chloro-2-phenylquinazoline (6) towards a variety of nitrogen and carbon nucleophiles is studied.
