313502-76-0

Basic information

• Product Name: Cyclopentanone, 3-(3-fluorophenyl)-4-(hydroxymethyl)-, (3S,4S)-
• CAS NO: 313502-76-0
• Molecular Formula: C12H13FO2
• Molecular Weight: 208.232
• Mol File: 313502-76-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Cyclopentanone, 3-(3-fluorophenyl)-4-(hydroxymethyl)-, (3S,4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanone, 3-(3-fluorophenyl)-4-(hydroxymethyl)-, (3S,4S)-(313502-76-0)
• EPA Substance Registry System: Cyclopentanone, 3-(3-fluorophenyl)-4-(hydroxymethyl)-, (3S,4S)-(313502-76-0)

Safety Data

• Hazardous Substances Data: 313502-76-0(Hazardous Substances Data)

Upstream product

• 313502-72-6 (+)-trans-1-(S)-hydroxymethyl-4-methylene-2-(S)-(3-fluorophenyl)cyclopentane 
• 301220-52-0 1-(t-Butoxycarbonyl)-4-((2-benzyl)-(2H)-tetrazol-5-yl)piperidine 
• 75-18-3 dimethylsulfide 
• 456-48-4 3-Fluorobenzaldehyde 
• 395065-66-4 (3S)-3-(3-fluorophenyl)-4-pentenoic acid 
• 335314-64-2 1-(3-fluorophenyl)-prop-2-enyl methyl carbonate 
• 395065-68-6 methyl (5S)-2-diazo-5-(3-fluorophenyl)3-oxo-6-heptenoate 
• 1026720-66-0 2-[(R)-1-(3-Fluoro-phenyl)-allyl]-malonic acid 
• 395065-67-5 methyl (5S)-5-(3-fluorophenyl)-3-oxo-6-heptenoate 

Downstream Products

• 313994-31-9 N-methyl-N-(1-(S)-3-(S)-hydroxymethyl-4-(S)-(3-fluorophenyl)cyclopent-1-yl)-(R)-valine t-butyl ester 
• 313980-11-9 N-methyl-N-(1-(R)-3-(S)-hydroxymethyl-4-(S)-(3-fluorophenyl)cyclopent-1-yl)-(R)-valine t-butyl ester 
• 313708-35-9 (+)-trans-1-t-butyldimethylsilyloxymethyl-4-oxo-2-(3-fluorophenyl)cyclopentane 
• 882980-73-6 N-(1-(S)-3-(S)-hydroxymethyl-4-(S)-(3-fluorophenyl)cyclopent-1-yl)-(R)-valine t-butyl ester 
• 313980-10-8 N-(1-(R)-3-(S)-hydroxymethyl-4-(S)-(3-fluorophenyl)cyclopent-1-yl)-(R)-valine t-butyl ester 

Relevant articles and documents

Alkyl C-O ring cleavage of bicyclic β-lactones with normant reagents: Synthesis of a merck IND intermediate

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Cyclopentyl modulators of chemokine receptor activity

The present invention is directed to compounds of the formula I: (wherein R1, R2, R3, R4, R5, R7, R8, X, n, x and y are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-5 and/or CCR-3.

Cyclopentyl modulators of chemokine receptor activity

The present invention is directed to compounds of the formula I: (wherein R1, R2, R3, R4, R5, R7, R8, X, n, x and y are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-5 and/or CCR-3.