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An improved synthesis of 1,2,4-triazoles using Ag2CO3
Paulvannan,Chen, Tao,Hale, Ron
, p. 8071 - 8076 (2007/10/03)
An improved synthesis of 1,3,5-trisubstituted 1,2,4-triazoles via Ag2CO3 mediated cyclization of triazenes has been developed. This approach is flexible and compatible with a wide range of functional groups. The reaction was complete within 3 h and the products were isolated in moderate to high yields. The influence of the β-substituents of the amines on the triazole formation was also studied. (C) 2000 Elsevier Science Ltd.
