313657-71-5

Usage

Uses

Since no specific applications or uses of 2-(2-Bromopyridin-3-yloxy)ethanol are widely reported, its use might be highly specialized. However, based on its chemical structure and properties, it can be hypothesized that it may have the following potential applications:
Used in Chemical Research:
2-(2-Bromopyridin-3-yloxy)ethanol is used as a research compound for studying its chemical properties, reactivity, and potential interactions with other molecules. Its unique functional groups may offer insights into new chemical reactions or mechanisms.
Used in Pharmaceutical Industry:
2-(2-Bromopyridin-3-yloxy)ethanol is used as a chemical intermediate in the synthesis of pharmaceutical compounds. Its bromopyridin-3-yl group and ethoxy group may be involved in the formation of active pharmaceutical ingredients or drug candidates with potential therapeutic applications.
Used in Agrochemical Industry:
2-(2-Bromopyridin-3-yloxy)ethanol is used as a precursor or intermediate in the synthesis of agrochemicals, such as pesticides or herbicides. Its chemical properties may contribute to the development of new and effective agrochemical products.
Used in Material Science:
2-(2-Bromopyridin-3-yloxy)ethanol is used as a component in the development of new materials with specific properties, such as conductivity, magnetism, or catalytic activity. Its functional groups may play a role in the formation of these materials and their desired characteristics.

InChI:InChI=1/C7H8BrNO2/c8-7-6(11-5-4-10)2-1-3-9-7/h1-3,10H,4-5H2

Upstream product

• 6602-32-0 2-bromo-pyridin-3-ol 
• 540-51-2 2-bromoethanol 
• 96-49-1 [1,3]-dioxolan-2-one 

Relevant academic research and scientific papers

Sequential alcohol oxidation/putative homo Claisen-Tishchenko-type reaction to give esters: A key process in accessing novel biologically active lactone macrocycles

We report an efficient methodology for the direct oxidative esterification of primary alcohols to diether-esters using pyridinium chlorochromate (PCC). Numerous studies were carried out to probe the reaction mechanism and at the same time optimize the reaction conditions. The reaction could be conducted with 1 equivalent of PCC and 1 equivalent of BF3·OEt2. Indications based on literature precedent were that the reaction may proceed via a sequential alcohol oxidation to the aldehyde followed by a putative Cr or boron catalyzed Claisen-Tishchenko-type reaction. Using this efficient methodology, we synthesized a family of novel diether-esters in very good yields; some of these molecules were subsequently tested against both acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). In addition, we also disclose a new synthetic strategy for the synthesis of lactam macrocycles with potential biological activity. This methodology included the regioselective borylation of the ester substrate and a subsequent Suzuki-Miyaura coupling to obtain the desired lactam macrocycle.

Intermediates for macrocyclic compounds

The present invention is directed to novel macrocyclic compounds of formula (I) and their pharmaceutically acceptable salts, hydrates or solvates: wherein R1, R2, R3, R4, R5, R6, n1, m, p Z1, Z2, and Z3 are as describe in the specification. The invention also relates to compounds of formula (I) which are antagonists of the motilin receptor and are useful in the treatment of disorders associated with this receptor and with or with motility dysfunction.

Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases

Compounds of the general formula (I): wherein the variables are as defined in the specification are useful for the prophylaxis or treatment of serotonin-related, especially 5-HT2receptor-related, diseases in human beings or animals, particularly diseases related to the 5-HT2creceptor, especially diseases such as eating disorders, memory disorders, schizophrenia, mood disorders, anxiety disorders, pain, sexual dysfunctionions, and urinary disorders.