313695-70-4

Usage

Uses

Used in Pharmaceutical Development:
N-[(1S,2S)-2-amino-1,2-diphenylethyl]-N'-[(1R)-1-(1-naphthalenyl)ethyl]-thiourea is used as a potential therapeutic agent for the treatment of various diseases and conditions, including cancer, diabetes, and inflammatory disorders. Its unique binding properties and structural features contribute to its potential as a drug candidate.
Used in Scientific Research:
In the scientific research industry, N-[(1S,2S)-2-amino-1,2-diphenylethyl]-N'-[(1R)-1-(1-naphthalenyl)ethyl]-thiourea is employed as a chemical compound for studying its pharmacological potential and exploring its possible therapeutic applications. Further studies are needed to fully understand its properties and effectiveness in treating specific diseases and conditions.

Upstream product

• 3886-70-2 (R)-1-(1-Naphthyl)ethylamine 

Downstream Products

• 313695-81-7 N-[(1S,2S)-2-tert-butoxycarbonylamino-1,2-diphenylethyl]-N'-[(R)-1-(1-naphthyl)ethyl]thiourea 
• 313695-94-2 (4S,5S)-1-tert-butoxycarbonyl-4,5-diphenyl-2-[(R)-1-(1-naphthyl)ethylimino]imidazolidine 

Relevant academic research and scientific papers

Highly enantioselective addition of ketones to nitroolefins catalyzed by new thiourea-amine bifunctional organocatalysts

A new and effective organocatalytic system: primary amine derived chiral thiourea catalyst 4a and AcOH-H2O additive, which converts different ketones to γ-nitroketones in high yields (82-99%) and enantioselectivities (90-99%) has been described

Modified guanidines as potential chiral superbases. 2. Preparation of 1,3-unsubstituted and 1-substituted 2-iminoimidazolidine derivatives and a related guanidine by the 2-chloro-1,3-dimethylimidazolinium chloride-induced cyclization of thioureas

Simple preparation methods for modified guanidines were explored for new chiral superbases. Thus, (4S,5S)-4,5-diphenyl- and diastereomeric cyclohexane-fused 2-iminoimidazolidines were prepared from (1S,2S) - 1,2 -diphenylethylenediamine and (1R,2R)- or (1S,2S)-1,2-diaminocyclohexanes through cyclization of protected thiourea intermediates with 2-chloro-1,3-dimethylimidazolinium chloride (DMC) as a key reaction. In the (4S,5S)-4,5-diphenyl series 1-methyl-2-iminoimidazolidines and 2-diethylaminoimidazoline were also prepared as related guanidines.