313963-39-2

Upstream product

• 586-96-9 Nitrosobenzene 
• 4541-14-4 4-benzyloxy-butan-1-ol 
• 313963-26-7 (5S)-3-[(E)-4-benzyloxybut-1-enyl]-2,5-dihydro-5-methylfuran-2-one 
• 313963-35-8 (E)-tert-butyl-6-benzyloxyhex-2-enoate 
• 100-39-0 benzyl bromide 
• 5470-84-8 4-benzyloxybutanal 
• 313963-38-1 (3S,6R,9R)-6-(2'-benzyloxy)-ethyl-3-methyl-4-phenyl-1,3,4,5,6,9-hexahydro-4-aza-5-oxoisobenzofuran-1-one 

Downstream Products

• 848565-55-9 (4R,5S)-3-[(R)-4-Benzyloxy-2-methoxymethoxy-but-(E)-ylidene]-5-methyl-4-phenylamino-dihydro-furan-2-one 
• 313963-41-6 (2'S,3R,4R,5S)-3-(4'-benzyloxy-2'-tert-butyldimethylsilyloxy)butyl-4-N-phenyl-N-trifluoroacetamido-2,3,4,5-tetrahydro-5-methylfuran-2-one 
• 313963-42-7 (E)-(2'S,3R,4R,5S)-3-(5'-iodo-2'-tert-butyldimethylsilyloxy)pent-4'-enyl-N-phenyl-N-trifluoroacetamido-2,3,4,5-tetrahydro-5-methylfuran-2-one 
• 313963-50-7 (2'S,3R,4R,5S)-3-(4'-hydroxy-2'-tert-butyldimethylsilyloxy)butyl-4-N-phenyl-N-trifluoroacetamido-2,3,4,5-tetrahydro-5-methylfuran-2-one 
• 313963-40-5 (2'S,3R,4R,5S)-3-(4'-benzyloxy-2'-tert-butyldimethylsilyloxy)butyl-4-N-phenylamino-2,3,4,5-tetrahydro-5-methylfuran-2-one 
• 443304-00-5 N-{4-[2-(tert-butyl-dimethyl-silanyloxy)-4-oxo-butyl]-2-methyl-5-oxo-tetrahydro-furan-3-yl}-2,2,2-trifluoro-N-phenyl-acetamide 
• 848565-39-9 N-[(2S,3R,4R)-4-((S)-4-Benzyloxy-2-methoxymethoxy-butyl)-2-methyl-5-oxo-tetrahydro-furan-3-yl]-2,2,2-trifluoro-N-phenyl-acetamide 
• 848565-48-0 2,2,2-Trifluoro-N-[(2S,3R,4R)-4-((S)-4-hydroxy-2-methoxymethoxy-butyl)-2-methyl-5-oxo-tetrahydro-furan-3-yl]-N-phenyl-acetamide 
• 848565-49-1 2,2,2-Trifluoro-N-[(2S,3R,4R)-4-((S)-2-methoxymethoxy-4-oxo-butyl)-2-methyl-5-oxo-tetrahydro-furan-3-yl]-N-phenyl-acetamide 
• 848565-54-8 (3R,4R,5S)-3-((S)-4-Benzyloxy-2-methoxymethoxy-butyl)-5-methyl-4-phenylamino-dihydro-furan-2-one 
• 313963-49-4 (2'R,4R,5S)-3-(4'-benzyloxy-2'-(tert-butyldimethylsilyloxy)butylidene)-4-N-phenylaminodihydro-5-methylfuran-2-one 

Relevant academic research and scientific papers

The total synthesis of the annonaceous acetogenin 10-hydroxyasimicin

Orthogonal and modular templating is an effective basis for the preparation of the biologically active annonaceous acetogenin 10-hydroxyasimicin (1). The versatile tartrate-derived 2,3-butanediacetal building block together with a highly diastereoselectiv

The total synthesis of the annonaceous acetogenin, muricatetrocin C

The total synthesis of the potential antitumour agent muricatetrocin C has provided an ideal stage for the exploitation and development of new chemistry. A convergent synthetic strategy has been realised incorporating three distinct pieces of methodology, these include a highly diastereoselective hetero-Diels -Alder reaction to construct the butenolide terminus, an oxygen to carbon rearrangement to install the trans-2,5-disubstituted tetrahydrofuran ring and a spatial desymmetrisation process to afford the anti-diol unit.