314045-13-1Relevant academic research and scientific papers
A three-component reaction for diversity-oriented synthesis of polysubstituted piperidines: Solution and solid-phase optimization of the first tandem aza [4+2]/allylboration
Toure, Barry B.,Hoveyda, Hamid R.,Tailor, Jyoti,Ulaczyk-Lesanko, Agnieszka,Hall, Dennis G.
, p. 466 - 474 (2003)
This article describes the design and optimization of a simple three-component aza[4+2]/allylboration reaction to access polysubstituted α-hydroxyalkyl piperidines in a highly diastereo-controlled fashion from maleimides, 4- boronohydrazonodienes, and ald
Tandem Aza[4 + 2]/allylboration: A novel multicomponent reaction for the stereocontrolled synthesis of α-hydroxyalkyl piperidine derivatives
Tailor, Jyoti,Hall, Dennis G.
, p. 3715 - 3718 (2000)
(matrix presented) The α-hydroxyalkyl piperidine unit is common to several naturally occurring alkaloids and azasugar analogues. Polysubstituted piperidine derivatives of this kind (3), embodying four stereogenic centers, are formed in just a single opera
