31408-97-6Relevant academic research and scientific papers
An alternative approach to the synthesis of [1,2,4]triazolo[1,5-a]pyridine-8-carbonitriles, their crystal structure, and DFT calculations
Khomenko, Dmytro M.,Shokol, Tetyana V.,Doroshchuk, Roman O.,Starova, Viktoriia S.,Raspertova, Ilona V.,Shova, Sergiu,Lampeka, Rostyslav D.,Volovenko, Yulian M.
, p. 1278 - 1285 (2021)
New representatives of [1,2,4]triazolo[1,5-a]pyridine-8-carbonitriles were synthesized via the condensation of β-diketones or β-dialdehydes and characterized using MS spectrometry, 1H, 13C and, 19F NMR and IR spectroscopy. Crystal structures of two compounds were established using X-ray analysis and showed that title compounds are prone to the formation of planar molecules. The absence of band responsible for CN stretching vibration in trifluoromethyl-containing compounds was explained using the DFT calculations method, which also showed a significant influence of fluorines introducing on the energy gap between HOMO and LUMO.
A Novel, One-Step Synthesis of Triazolopyridine Derivatives
Phadke, R. C.,Rangnekar, D. W.
, p. 860 - 862 (2007/10/02)
A novel, simple, one-step synthesis of previously unknown 2-substituted 4-cyano-5,7-dimethyl-triazolopyridine derivatives was achieved by reacting 1-amino-3-cyano-4,6-dimethyl-2-pyridone with various aliphatic, aromatic and heterocyclic amides.
