314289-74-2

Upstream product

• 314289-69-5 (5-benzyloxy-2-hydroxy-1,2,3,4-tetrahydronaphth-2-yl)methanol 
• 432036-81-2 (-)-(1S,4R)-camphanic acid [(5-benzyloxy-2-hydroxy-1,2,3,4-tetrahydronaphth-2-yl)methyl]ester 
• 432036-82-3 (-)-(1S,4R)-camphanic acid [((2R)-5-benzyloxy-2-hydroxy-1,2,3,4-tetrahydronaphth-2-yl)methyl]ester 
• 28315-93-7 5-Hydroxy-1-tetralone 
• 432036-83-4 ((2R)-5-benzyloxy-2-hydroxy-1,2,3,4-tetrahydronaphth-2-yl)methanol 
• 90401-60-8 5-benzyloxy-1,2,3,4-tetrahydro-naphthalen-1-one 
• 83-01-2 diphenylcarbamic chloride 
• 314289-73-1 diphenylcarbamic acid [((2R)-5-benzyloxy-2-hydroxy-1,2,3,4-tetrahydronaphth-2-yl)methyl]ester 
• 211805-74-2 5-(benzyloxy)-1,2,3,4-tetrahydronaphthalen-1-ol 
• 432036-78-7 5-benzyloxy-3,4-dihydronaphthalene 
• 432036-80-1 5-benzyloxy-1,23,4-tetrahydrospiro[naphthalene-2,2'-oxirane] 
• 432036-79-8 5-benzyloxy-1,2,3,4-tetrahydro-2-oxonaphthalene 
• 314289-66-2 4-benzyloxy-1a,2,3,7b-tetrahydronaphtho[1,2-b]oxirane 
• 172937-68-7 5-(tert-butyl-diphenyl-silanyloxy)-2-hydroxymethyl-1,2,3,4-tetrahydro-naphthalen-2-ol 

Downstream Products

• 172936-73-1 (2R)-2-hydroxy-2-(N,N-diphenylcarbamoyloxymethyl)-5-ethoxycarbonylmethoxy-1,2,3,4-tetrahydronaphthalene 

Relevant academic research and scientific papers

Practical synthesis of PGI2 agonist: Resolution-inversion- recycle approach of its chiral intermediate

Practical synthesis of ((2R)-5-benzyloxy-2-hydroxy-1,2,3,4- tetrahydronaphth-2-yl)methanol ((R)-7b), a key chiral intermediate for the synthesis of the novel PGI2 agonist, (R)-[6-[(diphenylcarbamoyloxy) methyl]-6-hydroxy-5,6,7,8-tetrahydronapht

Discovery of diphenylcarbamate derivatives as highly potent and selective IP receptor agonists: Orally active prostacyclin mimetics. Part 3

The new classes of diphenylcarbamate derivatives with a tetrahydronaphthalene skeleton as highly potent and selective IP agonists have been discovered. The optimized diphenylcarbamate type compound FK-788: (R)-4 exhibited potent antiaggregative potency wi