172936-73-1

Basic information

• Product Name: (2R)-2-hydroxy-2-(N,N-diphenylcarbamoyloxymethyl)-5-ethoxycarbonylmethoxy-1,2,3,4-tetrahydronaphthalene
• Synonyms: (2R)-2-hydroxy-2-(N,N-diphenylcarbamoyloxymethyl)-5-ethoxycarbonylmethoxy-1,2,3,4-tetrahydronaphthalene
• CAS NO: 172936-73-1
• Molecular Weight: 475.541
• Mol File: 172936-73-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2R)-2-hydroxy-2-(N,N-diphenylcarbamoyloxymethyl)-5-ethoxycarbonylmethoxy-1,2,3,4-tetrahydronaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-2-hydroxy-2-(N,N-diphenylcarbamoyloxymethyl)-5-ethoxycarbonylmethoxy-1,2,3,4-tetrahydronaphthalene(172936-73-1)
• EPA Substance Registry System: (2R)-2-hydroxy-2-(N,N-diphenylcarbamoyloxymethyl)-5-ethoxycarbonylmethoxy-1,2,3,4-tetrahydronaphthalene(172936-73-1)

Safety Data

• Hazardous Substances Data: 172936-73-1(Hazardous Substances Data)

Upstream product

• 314289-74-2 diphenylcarbamic acid ((2R)-2,5-dihydroxy-1,2,3,4-tetrahydronaphth-2-yl)methyl ester 
• 105-36-2 ethyl bromoacetate 
• 172937-73-4 (2R)-2-hydroxy-2-(N,N-diphenylcarbamoyloxymethyl)-5-t-butyldiphenylsilyloxy-1,2,3,4-tetrahydronaphthalene 
• 584-08-7 potassium carbonate 
• 432036-78-7 5-benzyloxy-3,4-dihydronaphthalene 
• 211805-74-2 5-(benzyloxy)-1,2,3,4-tetrahydronaphthalen-1-ol 
• 314289-73-1 diphenylcarbamic acid [((2R)-5-benzyloxy-2-hydroxy-1,2,3,4-tetrahydronaphth-2-yl)methyl]ester 
• 83-01-2 diphenylcarbamic chloride 
• 90401-60-8 5-benzyloxy-1,2,3,4-tetrahydro-naphthalen-1-one 
• 432036-83-4 ((2R)-5-benzyloxy-2-hydroxy-1,2,3,4-tetrahydronaphth-2-yl)methanol 
• 28315-93-7 5-Hydroxy-1-tetralone 
• 432036-82-3 (-)-(1S,4R)-camphanic acid [((2R)-5-benzyloxy-2-hydroxy-1,2,3,4-tetrahydronaphth-2-yl)methyl]ester 
• 432036-81-2 (-)-(1S,4R)-camphanic acid [(5-benzyloxy-2-hydroxy-1,2,3,4-tetrahydronaphth-2-yl)methyl]ester 
• 314289-69-5 (5-benzyloxy-2-hydroxy-1,2,3,4-tetrahydronaphth-2-yl)methanol 

Downstream Products

• 172936-64-0 sodium salt of [5-(carboxymethoxy)-2-hydroxy-1,2,3,4-tetrahydro-2-naphthyl]methyl N,N-diphenylcarbamate 

Relevant articles and documents

Practical synthesis of PGI2 agonist: Resolution-inversion- recycle approach of its chiral intermediate

Practical synthesis of ((2R)-5-benzyloxy-2-hydroxy-1,2,3,4- tetrahydronaphth-2-yl)methanol ((R)-7b), a key chiral intermediate for the synthesis of the novel PGI2 agonist, (R)-[6-[(diphenylcarbamoyloxy) methyl]-6-hydroxy-5,6,7,8-tetrahydronapht

Naphthalene derivatives as prostaglandin I2 agonsists

A compound of the formula STR1 wherein R1 is carboxy or protected carboxy, R2 is hydrogen, hydroxy or protected hydroxy, R3 is hydrogen, hydroxy, protected hydroxy, etc., R4 is hydrogen or halogen, A1