31431-10-4

Basic information

• Product Name: 5-Methylsulfanyl-2-nitroaniline
• Synonyms: 5-Methylsulfanyl-2-nitroaniline
• CAS NO: 31431-10-4
• Molecular Weight: 184.219
• Mol File: 31431-10-4.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 5-Methylsulfanyl-2-nitroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methylsulfanyl-2-nitroaniline(31431-10-4)
• EPA Substance Registry System: 5-Methylsulfanyl-2-nitroaniline(31431-10-4)

Safety Data

• Hazardous Substances Data: 31431-10-4(Hazardous Substances Data)

Usage

Uses

5-Methylsulfanyl-2-nitroaniline is an intermediate in the synthesis of metabolites of Albendazole (A511610).

Upstream product

• 2369-11-1 5-fluoro-2-nitroaniline 
• 5188-07-8 sodium thiomethoxide 
• 5443-33-4 N-(5-chloro-2-nitrophenyl)acetamide 
• 1635-61-6 5-chloro-2-nitroaniline 
• 701-57-5 1-methylthio-4-nitro-benzene 
• 857786-53-9 bis-(3-acetylamino-4-nitro-phenyl)-disulfide 

Downstream Products

• 119982-65-9 (3-chloro-4-nitrophenyl)(methyl)sulfane 
• 121444-20-0 5-(methylsulfonyl)-2-nitroaniline 
• 960000-79-7 methyl 5-(5-(methylsulfonyl)-1H-benzimidazol-1-yl)-3-((phenylmethyl)oxy)-2-thiophenecarboxylate 
• 960000-77-5 methyl 5-(5-(methylthio)-1H-benzimidazol-1-yl)-3-((phenylmethyl)oxy)-2-thiophenecarboxylate 
• 121537-61-9 6-(methylthio)-1H-benzimidazole 
• 67469-02-7 4-methylsulfanylbenzene-1,2-diamine 
• 20901-66-0 2-chloro-4-methylthiobenzeneamine 

Relevant articles and documents

Benzimidazole derivatives, their preparation and their application in medicine and pharmacology (by machine translation)

The invention relates to a new control or inhibit indocyanine 2, 3 - dioxygenase (IDO) activity of the benzimidazole derivatives, their preparation and their application in medicine and pharmacology. Specifically, the invention relates to a compound of general formula (I) compound of formula and its pharmaceutically acceptable salt, containing the compound or its pharmaceutically acceptable salt of the pharmaceutical composition, the use of the compound or its pharmaceutically acceptable salts for treating and/or preventing the relevance of the IDO-mediated disease, especially a tumor of the method and the compound or its pharmaceutically acceptable salts thereof. The invention also relates to the compound or its pharmaceutically acceptable salt or containing the compound or its pharmaceutically acceptable salts for the preparation of a pharmaceutical composition for treating and/or preventing the relevance of the IDO-mediated disease, in particular of the use of the drug in the tumor. Wherein the general formula (I) of each substituent is as defined in the specification. (by machine translation)

METHODS USING HDAC11 INHIBITORS

The present invention provides methods and uses of inhibitors of histone deacetylase 11 (HDAC11) in the treatment of diseases and/or disorders, such as, for example, cell proliferative diseases.

Benzimidazole Thiophene Compounds

The present invention provides benzimidazole thiophene compounds pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.