3145-88-8

Basic information

• Product Name: 1,2-CYCLOPENTANEDIAMINE
• Synonyms: 1,2-CYCLOPENTANEDIAMINE;Cyclopentane-1,2-diaMine;(1R,2R)-rel-Cyclopentane-1,2-diamine;trans-cyclopentane-1,2-diamine
• CAS NO: 3145-88-8
• Molecular Formula: C5H12N2
• Molecular Weight: 100.16
• Mol File: 3145-88-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 165.1°Cat760mmHg
• Flash Point: 60.2°C
• Appearance: /
• Density: 0.964g/cm³
• Vapor Pressure: 1.91mmHg at 25°C
• Refractive Index: 1.492
• PKA: 10.70±0.40(Predicted)
• CAS DataBase Reference: 1,2-CYCLOPENTANEDIAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-CYCLOPENTANEDIAMINE(3145-88-8)
• EPA Substance Registry System: 1,2-CYCLOPENTANEDIAMINE(3145-88-8)

Safety Data

• Hazardous Substances Data: 3145-88-8(Hazardous Substances Data)

Usage

General Description

1,2-Cyclopentanediamine is a chemical compound with the formula C5H12N2. It is a cyclic diamine, also known as cyclopentane-1,2-diamine, that consists of a five-membered carbon ring with two amino groups. 1,2-CYCLOPENTANEDIAMINE is used primarily in the production of various polymers and resins, as well as in the manufacturing of pharmaceuticals and agrochemicals. It also serves as a precursor for the synthesis of other organic compounds and is widely utilized for its versatile chemical reactivity. 1,2-Cyclopentanediamine is a key intermediate in the production of numerous products across different industries, making it an important chemical in the field of organic synthesis.

InChI:InChI=1/C5H12N2/c6-4-2-1-3-5(4)7/h4-5H,1-3,6-7H2/t4-,5-/m1/s1

Upstream product

• 6635-29-6 cyclopentane-1,2-dione dioxime 
• 287-92-3 Cyclopentane 
• 10230-26-9 trans-1,2-dibromocyclopentane 
• 5057-99-8 trans-cyclopentane-1,2-diol 
• 142-29-0 cyclopentene 
• 1461-96-7 Cyclopentan-1,2-trans-dicarbonsaeure 

Downstream Products

• 1417905-86-2 1,2-trans-diaminocyclopentane diiodoplatinum(II) 
• 1193388-07-6 (1R*,2R*)-2-aminocyclopentylcarbamic acid tert-butyl ester 
• 1193388-07-6 tert-butyl rac-trans-(2-aminocyclopentyl)carbamate 

Relevant articles and documents

A method for the treatment of tumor cell proliferative diseases of platinum (II) compound

Disclosed are a platinum compound with the leaving group malonic derivative "2" position substituent containing a primary amino, a secondary amino, a tertiary amino, and a quaternary amino, as well as pharmaceutically acceptable salt, preparation method thereof, and pharmaceutical composition containing the compound. Also disclosed are uses of the compound for treating cell proliferative diseases, particularly cancers. The platinum compound of the present invention has the high water solubility and the low toxicity.

PLATINUM COMPOUND HAVING AMINO OR ALKYLAMINO-CONTAINING SUCCINIC ACID DERIVATIVES AS LEAVING GROUP, PREPARTION METHOD THEREOF, AND USE THEREOF

Disclosed are a category of platinum compounds having amino- or alkylamino-containing succinato derivatives as leaving group, or pharmaceutically acceptable salts thereof, preparation method thereof, and medicinal compositions containing the compounds. Also disclosed is a use of the compounds in treating cell proliferative diseases, especially cancers. The platinum compounds of the present invention have high water solubility and small toxic side effect.

Synthesis of two stereoisomeric polydentate ligands, trans and cis cyclopentane-1,2-diaminotetraacetic acids, and complexation by 111In and 153Sm

Two polyaminocarboxylic acid chelating agents were synthesized. Complexation properties regarding 111In and 153Sm, two radionuclides suitable for applications in immunoscintigraphy and radioimmunotherapy were investigated. The synthesis of aminodiacetic acid derivatives 7a and 7b involved preliminary stereoselective synthesis of the corresponding amines, cis and trans cyclopentane-1,2-diamines. 111In labelling confirmed the complexation abilities of the two ligands. An additional comparative study to probe the relationship between ligand structure and metal complex was performed with 153Sm.