314728-05-7Relevant academic research and scientific papers
Inhibition of trypanothione reductase by substrate analogues.
Garrard,Borman,Cook,Pike,Alberg
, p. 3639 - 3642 (2000)
Trypanothione reductase (TR) catalyzes the NAPDH-dependent reduction of the spermidine-glutathione conjugate trypanothione, an antioxidant found in Trypanosomatid parasites. TR plays an essential role in the parasite's defense against oxidative stress and
