314728-04-6

Basic information

• Product Name: (S)-2-benzyloxycarbonylamino-4-hydroxybutyric acid methyl ester
• Synonyms: (S)-2-benzyloxycarbonylamino-4-hydroxybutyric acid methyl ester
• CAS NO: 314728-04-6
• Molecular Weight: 267.282
• Mol File: 314728-04-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: (S)-2-benzyloxycarbonylamino-4-hydroxybutyric acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-benzyloxycarbonylamino-4-hydroxybutyric acid methyl ester(314728-04-6)
• EPA Substance Registry System: (S)-2-benzyloxycarbonylamino-4-hydroxybutyric acid methyl ester(314728-04-6)

Safety Data

• Hazardous Substances Data: 314728-04-6(Hazardous Substances Data)

Upstream product

• 35677-88-4 N-benzyloxycarbonyl-(L)-homoserine 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 35677-89-5 benzyl (3S)-2-oxotetrahydro-3-furanylcarbamate 
• 4668-37-5 N-(benzyloxycarbonyl)asparagine methyl ester 
• 2304-96-3 N-benzyloxycarbonyl-L-asparagine 
• 58578-43-1 (S)-2-benzyloxycarbonylamino-4-hydroxybutyric acid dicyclohexylamine salt 
• 74-88-4 methyl iodide 
• 67-56-1 methanol 
• 501-53-1 benzyl chloroformate 
• 4668-42-2 (S)-2-benzyloxycarbonylamino-succinic acid 1-methyl ester 

Downstream Products

• 868285-96-5 (S )-methyl 2-(((benzyloxy)carbonyl)amino)-4-((methylsulfonyl)oxy)butanoate 
• 1417900-10-7 (4S)-4-[(benzyloxycarbonyl)amino]-4,5-dihydro-3(2H)-pyridazinone 
• 1417900-12-9 (4S)-4-[(benzyloxycarbonyl)amino]-tetrahydro-3(2H)-pyridazinone 
• 1417900-13-0 (4S)-4-[(benzyloxycarbonyl)amino]-2-methyl-tetrahydro-3(2H)-pyridazinone 
• 1417900-14-1 (4S)-4-[(benzyloxycarbonyl)amino]-tetrahydro-3-oxo-1(2H)-pyridazinecarboxamide 
• 1417900-15-2 (4S)-4-[(benzyloxycarbonyl)amino]-tetrahydro-2-methyl-3-oxo-1(2H)-pyridazinecarboxamide 
• 1417900-19-6 (4S)-4-[(benzyloxycarbonyl)amino]tetrahydro-2-methyl-3-oxo-1(2H)-pyridazinecarbonitrile 
• 1139269-96-7 ethyl L-2-[(benzyloxycarbonyl)amino]-3-iodopropanoate 
• 30134-53-3 S-4-Cyano-2-[[(phenylmethoxy)carbonyl]-amino]butanoic acid methyl ester 
• 634587-01-2 (3S,4S,5R)-1-O-(tert-butyldimethylsilyl)-3-[(benzyloxycarbonyl)amino]-4,5-nonadecanediol 
• 634587-04-5 (3S,4R,5S)-1-O-(tert-butyldimethylsilyl)-3-[(benzyloxycarbonyl)amino]-4,5-nonadecanediol 

Relevant articles and documents

Synthesis of desmosine-containing cyclic peptide for the possible elucidation of elastin crosslinking structure

Elastin is a vital extracellular matrix protein, which is known for providing elasticity in numerous tissues. It is formed by the self-assembly and subsequent crosslinking of elastin precursor, tropoelastin. Two tetrafunctional, pyridinium-based amino acids desmosine and isodesmosine are exclusively found in elastin and play an important role as crosslinkers. Structural elucidation of elastin has eluded scientists to date, owing to the highly cross-linked structure and insoluble nature. Therefore, in this study, we aimed to synthesize a desmosine-containing cyclic peptide as a partial elastin mimic, in order to eventually facilitate the elucidation of the crosslinking pattern of elastin by mass spectrometric analysis.

Light-mediated deoxygenation of alcohols with a dimeric gold catalyst

A new protocol for the reductive deoxygenation of primary alcohols was explored. This photo-mediated method combines a novel approach to bromination of alcohols merged with the powerful reducing capability of [Au2(dppm)2]Cl2 [dppm = 1,1-bis(diphenylphosphino)methane] as a photoredox catalyst. The highly efficient methods discussed are marked by the use of UVA light-emitting diodes, which have significantly reduced reaction times and lowered setup cost.

An access to aza-Freidinger lactams and E-locked analogs

Freidinger lactams, possessing a peptide bond configuration locked to Z, are important key elements of conformationally restricted peptidomimetics. In the present work, the CαHi+1 unit has been replaced by N, leading to novel aza-Fre