60684-59-5

Upstream product

• 688-73-3 tri-n-butyl-tin hydride 
• 4668-37-5 N-(benzyloxycarbonyl)asparagine methyl ester 
• 2304-96-3 N-benzyloxycarbonyl-L-asparagine 
• 501-53-1 benzyl chloroformate 
• 78553-47-6 methyl (2S)-2-[N-(benzyloxycarbonyl)amino]pent-4-enoate 
• 78553-51-2 (S)-2-(benzyloxycarbonylamino)pent-4-enoic acid 
• 4668-42-2 (S)-2-benzyloxycarbonylamino-succinic acid 1-methyl ester 
• 314728-04-6 (S)-2-benzyloxycarbonylamino-4-hydroxybutyric acid methyl ester 
• 186581-53-3 diazomethane 
• 60655-04-1 (S)-N-Cbz-aspartic acid semialdehyde 
• 153413-52-6 (S)-2-benzyloxycarbonylamino-3-chlorocarbonyl-propionic acid methyl ester 
• 78553-52-3 (S)-2-Benzyloxycarbonylamino-4,5-dihydroxy-pentanoic acid methyl ester 

Downstream Products

• 314728-05-7 methyl (2S,4E)-2-(benzyloxycarbonylamino)-6-oxohex-4-enoate 
• 314728-07-9 methyl (2S,4E)-2-(benzyloxycarbonylamino)-6-bromohex-4-enoate 
• 314728-06-8 methyl (2S,4E)-2-(benzyloxycarbonylamino)-6-hydroxyhex-4-enoate 
• 314728-11-5 (E)-(2S,7S)-2-Amino-7-benzyloxycarbonylamino-oct-4-enedioic acid dimethyl ester 
• 314728-10-4 (2S,5R,2'E,5'S)-2-[5'-(benzyloxycarbonylamino)-5'-carbomethoxy-pent-2-ene]-2,5-dihydro-5-isopropyl-3,6-dimethyloxypyrazine 
• 314728-13-7 (2S,4E,7S)-2,7-bis(benzyloxycarbonylamino)oct-4-en-1,8-dioic acid 
• 314728-12-6 dimethyl (2S,4E,7S)-2,7-bis(benzyloxycarbonylamino)oct-4-en-1,8-dioate 
• 314728-14-8 ((E)-(1S,6S)-6-Benzyloxycarbonylamino-1,6-bis-{[(3-dimethylamino-propylcarbamoyl)-methyl]-carbamoyl}-hex-3-enyl)-carbamic acid benzyl ester 
• 314728-20-6 {(E)-(1S,6S)-6-Benzyloxycarbonylamino-1,6-bis-[({3-[(9H-fluoren-9-ylmethoxycarbonyl)-propyl-amino]-propylcarbamoyl}-methyl)-carbamoyl]-hex-3-enyl}-carbamic acid benzyl ester 
• 314728-22-8 {(1S,6S)-6-Benzyloxycarbonylamino-1,6-bis-[({3-[(9H-fluoren-9-ylmethoxycarbonyl)-propyl-amino]-propylcarbamoyl}-methyl)-carbamoyl]-hexyl}-carbamic acid benzyl ester 

Relevant academic research and scientific papers

An access to aza-Freidinger lactams and E-locked analogs

Freidinger lactams, possessing a peptide bond configuration locked to Z, are important key elements of conformationally restricted peptidomimetics. In the present work, the CαHi+1 unit has been replaced by N, leading to novel aza-Fre

Inhibition of trypanothione reductase by substrate analogues.

Trypanothione reductase (TR) catalyzes the NAPDH-dependent reduction of the spermidine-glutathione conjugate trypanothione, an antioxidant found in Trypanosomatid parasites. TR plays an essential role in the parasite's defense against oxidative stress and

PROCESS AND INTERMEDIATES FOR THE PREPARATION OF EXCITATORY AMINOACID RECEPTOR ANTAGONISTS

The present invention provides novel intermediates which are useful for the preparation of excitatory amino acid receptor antagonists. Further provided is a process to enatioselectively prepare hydroisoquinoline compounds with central nervous system activ

Intramolecular Diels-Alder Route To 6-octadecahydroisoquinoline-3-Carboxylates: Intermediates For The Synthesis Of Conformationally Constrained Excitatory Amino Acid Antagonists

We report the preparation of a hydroisoquinoline intermediate potentially useful for the synthesis of some excitatory amino acid antagonists.The requisite stereochemistry is established by an intramolecular Diels-Alder reaction, and the absolute stereochemistry is ultimately derived from S-aspartic acid.Also reported is an efficient synthesis of methyl N-CBZ asparate β-aldehyde.

SYNTHESIS OF NICOTIANAMINE AND A RELATED COMPOUND, DERIVATIVES OF AZETIDINE-2-CARBOXYLIC ACID

The synthesis of nicotianamine (1) and a related compound (2) - amino acid derivatives having the azetidine ring - was achieved by reductive coupling of L-aspartic-β-semialdehyde derivatives with L-azetidine-2-carboxylic acid methyl ester.

Research on substances with antiviral activity. V. Structural analogs of arginine

Some arginine analogues were synthesized and tested for antiviral activity. Two compounds showed weak activity in vitro against vaccinia virus.