31499-91-9

Basic information

• Product Name: 2-Acetyl-3-phenylisoxazol-5(2H)-one
• Synonyms: 2-Acetyl-3-phenylisoxazol-5(2H)-one
• CAS NO: 31499-91-9
• Molecular Weight: 203.197
• Mol File: 31499-91-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Acetyl-3-phenylisoxazol-5(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Acetyl-3-phenylisoxazol-5(2H)-one(31499-91-9)
• EPA Substance Registry System: 2-Acetyl-3-phenylisoxazol-5(2H)-one(31499-91-9)

Safety Data

• Hazardous Substances Data: 31499-91-9(Hazardous Substances Data)

Upstream product

• 1076-59-1 3-phenyl-4H-isoxazol-5-one 
• 75-36-5 acetyl chloride 
• 108-24-7 acetic anhydride 

Downstream Products

• 140-29-4 phenylacetonitrile 
• 20662-90-2 2-methyl-4-phenyloxazole 
• 100-47-0 benzonitrile 
• 103-84-4 Acetanilid 

Relevant articles and documents

Chemistry of 5-oxodihydroisoxazoles. Part 17. Acylation of 5-oxodihydroisoxazoles

2-Unsubstituted isoxazol-5(4H)-ones and -5(2H)-ones may be acylated by acid chlorides, anhydrides or carboxylic acids in the presence of carbodiimides, to give O- and N-acylated products. The solvent, the presence of base and the temperature are found to alter the product ratios dramatically, but the substituents present at C-3 have the greatest effect. Aliphatic acid anhydrides and chlorides generally react at nitrogen, but aroyl halides give significant proportions of O-acylated products. Limited success in converting O-aroyl to N-aroyl isoxazolones is reported.