31501-46-9Relevant articles and documents
MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF
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Page/Page column 111-112, (2021/02/19)
The present disclosure provides oligomeric compounds comprising a modified oligonucleotide having at least one stereo-non-standard nucleoside. An oligomeric compound comprising a modified oligonucleotide consisting of 12-30 linked nucleosides, wherein at least one nucleoside of the modified oligonucleotide is a stereo-non-standard nucleoside; and wherein the oligomeric compound is selected from among an RNAi compound, a modified CRISPR compound, and an artificial mRNA compound.
Total synthesis of 2'-O-methyl-β-L-arabinosyluridine and reassignment the nucleoside from penicillium sp. as 2'-O-methyl-β-L-uridine
Shen, Chunyang,Ding, Haixin,Tao, Xueping,Yang, Ruchun,Bai, Jiang,Cao, Ban-Peng,Peng, Yi-Yuan,Xiao, Qiang
, p. 68 - 72 (2020/01/30)
In order to validate the structure of a rarely reported naturally occurring nucleoside isolated from the broth of Penicillium sp. (NO. 64), practical syntheses of 2′-O-methyl-β-L-arabinosyluridine, 2′-O-methyl-α-L-arabinosyluridine, and 2′-O-methyl-β-L-uridine were accomplished. Comparing their nuclear magnetic resonance (NMR) spectra and physical data, its structure was reassigned as 2′-O-methyl-β-L-uridine instead of former reported 2′-O-methyl-β-L-arabinosyluridine.
Three-pronged probes: High-affinity DNA binding with cap, β-alanines and oligopyrrolamides
Haug, Ruediger,Kramer, Markus,Richert, Clemens
supporting information, p. 15822 - 15826 (2014/04/03)
TPP oligonucleotides: Hybridization probes that interrogate target sequences through base pairing, stacking on the terminus, and binding in the minor groove are presented (see figure). All subunits of the probes contribute to the target affinity, leading
