31510-02-8Relevant articles and documents
Intermolecular ritter-type C-H amination of unactivated sp3 carbons
Michaudel, Quentin,Thevenet, Damien,Baran, Phil S.
supporting information; experimental part, p. 2547 - 2550 (2012/04/04)
Intermolecular Ritter-type C-H amination of unactivated sp3 carbons has been developed. This new reaction proceeds under mild conditions using readily available reagents and an inexpensive source of nitrogen (acetonitrile). A broad scope of substrates can be aminated with this method since many functional groups are tolerated. This reaction also allows for the direct, innate C-H amination of a variety of hydrocarbons such as cyclohexane without the need of prefunctionalization or installation of a directing group.
Bicyclization of aza-compounds by positive halide ions. II. Lactams and some related cyclizations
Elofson, Richard M.,Gadallah, Fahmi F.,Laidler, James K.
, p. 2770 - 2773 (2007/10/02)
Anodic oxidation of lactams in the presence of halide ions produced excellent yields of bicyclic compounds with reactants having rings in the range of eight to ten atoms (C7 to C9).Smaller rings did not react to form bicyclic products and larger rings gave reduced yields.Attempts were made to cyclize non-cyclic amides and to bicyclize cycloheptyl and cyclooctyl acetamide with limited success.
