31519-50-3

Basic information

• Product Name: (S)-(-)-SEC-BUTYLAMINE HYDROCHLORIDE
• Synonyms: (S)-butan-2-amine hydrochloride;(S)-SEC-BUTYLAMINE HCL;2-Butanamine, hydrochloride, (2S)-
• CAS NO: 31519-50-3
• Molecular Formula: C₄H₁₂N*Cl
• Molecular Weight: 109.6
• Mol File: 31519-50-3.mol
• Article Data: 6

Chemical Properties

• Melting Point: 106-107 °C
• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: (S)-(-)-SEC-BUTYLAMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(-)-SEC-BUTYLAMINE HYDROCHLORIDE(31519-50-3)
• EPA Substance Registry System: (S)-(-)-SEC-BUTYLAMINE HYDROCHLORIDE(31519-50-3)

Safety Data

• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 31519-50-3(Hazardous Substances Data)

Usage

General Description

(S)-(-)-SEC-BUTYLAMINE HYDROCHLORIDE is a chemical compound often used as an intermediate in the manufacturing of pharmaceuticals, agrochemicals, and organic chemicals. It is a derivative of butylamine, and its hydrochloride form is a white crystalline solid with a melting point of around 210-213°C. It is known for its ability to selectively react with various functional groups, making it a versatile building block in organic synthesis. The compound is also used in the production of rubber chemicals, corrosion inhibitors, and surfactants. Additionally, (S)-(-)-SEC-BUTYLAMINE HYDROCHLORIDE has been studied for its potential applications in the treatment of neurodegenerative diseases and as a chiral auxiliary in asymmetric synthesis. However, it is important to handle this compound with care, as it can be toxic and hazardous if not properly managed.

Upstream product

• 2719-08-6 methyl 2-(acetylamino)benzoate 
• 142310-24-5 1-<(1-methylpropylidene)amino>-3-phenyl-4-methyl-5-methoxypyrazole 
• 102095-57-8 C₁₃H₂₈NO₅P 
• 76716-18-2 diphenylphosphinic 1-methylpropylamide 
• 146039-14-7 sec-Butyl-phosphorimidic acid triethyl ester 

Downstream Products

• 513-49-5 (S)-2-aminobutane 
• 556-02-5 tyrosine 
• 78-93-3 butanone 
• 673-06-3 D-(R)-phenylalanine 
• 640-68-6 D-Val-OH 
• 623154-17-6 N-(S)-sec-butyl-4-[(2-methyl-5-ethylcarbamoyl)aminophenyl]-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide 
• 427878-18-0 N-(S)-sec-butyl-4-(2-methyl-5-(methoxycarbamoyl)phenylamino)-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide 
• 64343-40-4 (S,S)-trans-1,2-diaminocyclohexane⁽²⁺⁾ 
• 31458-26-1 N-sec-Butyl-3,3,3-trifluoro-2-methoxy-2-phenyl-propionamide 
• 81038-91-7 3-sec-butylamino-1,2-benzisothiazole-1,1-dioxide 
• 83325-08-0 1,7-dihydro-2-methyl-1-(1-methylpropyl)-7-phenyl-6H-purin-6-one 
• 623-45-0 (S)-Butyl-⁽²⁾-isothiocyanat 
• 86217-79-0 sec-butyl isocyanate 

Relevant articles and documents

Optimized procedures for one-pot conversion of alkyl bromides into amines via the Staudinger reaction

New optimized procedures for transforming primary and secondary alkyl bromides into the corresponding primary amine salts have been elaborated. Essential modifications of azidation and deprotection of intermediate triethoxyphosphine alkylimides resulted in substantial improvement of the overall yields. Conversion of ammonium tosylates and hydrochlorides into free amines in a nonaqueous medium is described.

Conversion of Alcohols into Primary Amines, a New Mitsunobu Version of Gabriel-type Synthesis

Primaere und sekundaere Alkohole liefern die entsprechenden Amin-hydrochloride 3 mit guten Ausbeuten (60-85percent), wenn sie unter milden Bedingungen mit N-(Diethoxyphosphoryl)-carbamidsaeure-tert-butylester (1) in Gegenwart von Azodicarbonsaeure-diethylester/Triphenylphosphan umgesetzt und danach die entstandenen N-Alkyl-N-(diethoxyphosphoryl)carbamidsaeureester 2 mit gasfoermigem HCl gespalten werden.Die Stereochemie dieser Reaktion wird untersucht.

Phase-Transfer-Catalysed N-Alkylation of Diphenylphosphinamide and Diphenylphosphinanilide with Secondary Alkyl Bromides

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