623-45-0

Upstream product

• 75-15-0 carbon disulfide 
• 33966-50-6 SEC-BUTYLAMINE 
• 96989-50-3 di-2-pyridyl thionocarbonate 
• 14069-89-7 (+/-)sec-butyl isocyanide 
• 88064-52-2 1-(s-butyl)-2,4,6-triphenylpyridinium tiocyanate 
• 463-71-8 thiophosgene 
• 31519-50-3 (S)-1-methylpropylamine hydrochloride 

Downstream Products

• 31182-22-6 N_.N'-di-(sec-butyl)-thiourea 
• 33966-50-6 SEC-BUTYLAMINE 
• 513-49-5 (S)-2-aminobutane 
• 4312-11-2 4-sec-butyl-thiosemicarbazide 
• 6814-99-9 N-(sec-butyl)thiourea 
• 16885-29-3 N-((S)-sec-butyl)-N'-phenyl-thiourea 
• 32497-67-9 4-(N'-sec-Butyl-guanidino)-N-(4-chloro-phenyl)-benzamidine 
• 802328-69-4 1-sec-Butyl-3-{4-[N'-(4-chloro-phenyl)-guanidino]-phenyl}-thiourea 
• 51098-18-1 sec-Butyl-dithiocarbamic acid p-tolyl ester 
• 852675-21-9 R/S-N-(2-amino-5-methylsulfonylbenzenesulfonyl)-N'-2-butylthiourea 
• 14117-23-8 (S)-N-(sec-butyl)-N'-benzyl-urea 
• 767329-46-4 tert-butyl 2-{5-{[(sec-butylamino)carbonothioyl]amino}-2-[(3,4,5-trimethoxyphenyl)amino]-3H-imidazo[4,5-b]pyridin-3-yl}ethylcarbamate 
• 6814-99-9 (S)-1--thioharnstoff 

Relevant academic research and scientific papers

Direct, Microwave-Assisted Synthesis of Isothiocyanates

A microwave-assisted desulfuration of readily available dithiocarbamates, formed in situ from primary amines, leading to target isothiocyanates has been developed. This efficient protocol provides a rapid, environmentally benign route to aliphatic and aromatic isothiocyanates.

Novel selenium catalyzed synthesis of isothiocyanates from isocyanides and elemental sulfur

A variety of aliphatic and aromatic isothiocyanates were synthesized in good to excellent yields from corresponding isocyanides and elemental sulfur under mild conditions by use of catalytic amounts of elemental selenium.

Phosphine-Substituted Chelate Ligands, XXV. Diastereoselective Complexation of Chiral Phosphinothioformamides with Remote Asymmetric Centre

For further studies of the diastereoselective complex formation of ambidentate chiral chelating ligands, we prepared the racemic phosphinothioformamides, Ph2P(X)C(S)NHC*HR1R2, with X = 2e- (R1 = Ph, R2 = Et: 1a; R1 = Ph, R2 = iPr: 2a; R1 = Me, R2 = Et: 3a) and X = O (1b, 2b) according to a previously reported route.The coordination of 1a-3a to CpM(CO)3Cl (M = Mo, W) in methanol gives the diastereomeric P,S-chelate complexes, (Mo: 4-6, W :7-9).In solution, epimerisation proceeds to an equilibrium ratio of B/A = 1.5 in case of 4, 5, 7, and 8, but less than 1.1 with 6 and 9.A reduced diastereoselectivity (d.e. 10-20percent) is also observed during the formation of the analogous molybdenum complexes 10a-d with phosphine ligands derived from α-amino acid esters, Ph2PC(S)NHC*H(R)COOMe .The results indicate a significant asymmetric induction despite of the four bond distance of the chiral centres. - Diastereoselectivity, Chiral Phosphinothioformamides, Amino Acid Esters, Remote Asymmetric Centre, Cyclopentadienyl Molybdenum and Tungsten Complexes

DI-2-PYRIDYL THIONOCARBONATE. A NEW REAGENT FOR THE PREPARATION OF ISOTHIOCYANATES AND CARBODIIMIDES.

Reaction of amines with di-2-pyridyl thionocarbonate affords the corresponding isothiocyanates at room temperature, while reaction of N,N'-disubstituted thioureas with di-2-pyridyl thionocarbonate in the presence of 4-dimethylaminopyridine as a catalyst affords the corresponding carbodiimides in high yields.

Kinetics and Mechanism of Nucleophilic Displacements with Heterocycles as Leaving Groups. Part 10. Reactions of s-Alkyl Primary Amines with Pyryliums

2,4,6-Triphenylpyrylium with s-alkylamines gives isolatable pyridiniums (which undergo SN2 substitution with nucleophiles and elimination to olefins). 2,4,6-triphenylpyrilium with 1-phenylethylamine and α-phenylbenzylamine forms the corresponding carbonium ions which may be trapped by nucleophiles.Isolated 1-cycloalkylbenzoquinoliniums (2) solvolyse by the SN1 mechanism (for five-, six- and seven-membered rings): for the cyclobutyl case an Sn2 reaction is also found.