31535-05-4

Basic information

• Product Name: 3-chloro-2-methyltetrahydropyran
• Synonyms: 3-chloro-2-methyltetrahydropyran
• CAS NO: 31535-05-4
• Molecular Weight: 134.606
• Mol File: 31535-05-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-chloro-2-methyltetrahydropyran(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-2-methyltetrahydropyran(31535-05-4)
• EPA Substance Registry System: 3-chloro-2-methyltetrahydropyran(31535-05-4)

Safety Data

• Hazardous Substances Data: 31535-05-4(Hazardous Substances Data)

Upstream product

• 5631-95-8 2,3-dichlorotetrahydro-2H-pyran 
• 75-16-1 methylmagnesium bromide 
• 74-83-9 methyl bromide 

Downstream Products

• 10141-72-7 2-methyloxane 
• 16015-11-5 6-methyl-3,4-dihydro-2H-pyran 
• 55230-25-6 6-methyl-3,6-dihydro-2H-pyran 
• 928-92-7 (E)-hex-4-en-1-ol 
• 928-91-6 (Z)-4-hexenol 

Relevant articles and documents

THE STERIC COURSE OF THE REACTIONS OF 2,3-DIHALOTETRAHYDROPYRANS WITH GRIGNARD REAGENTS

The steric course of some reactions of 2,3-dihalotetrahydropyrans with sodium methoxide and with methyl- and phenyl-magnesium bromides has been reinvestigated.Whereas the methanolysis of the cis- and trans-dichlorides occurs with practically complete inversion, it has been confirmed that their reactions, as well as those of dibromides, with methylmagnesium bromide are non-stereospecific, yielding mixtures of trans- and cis-3-halo-2-methyl-tetrahydropyrans in ratios that are independent of the configurations of the starting dihalides.It has been further established that grignard reagents cause equlibration of cis- and trans-dihalide mixtures in a reaction that is much faster than the Grignard coupling step.