31545-35-4

Usage

Uses

Used in Pharmaceutical Industry:
N-(3,5-Dibromo-2-pyridyl)thiourea, 97% is used as an intermediate in the synthesis of organic compounds for the development of new drugs. Its unique structure and properties may contribute to the discovery of novel therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical field, N-(3,5-Dibromo-2-pyridyl)thiourea, 97% is used as a building block in the creation of new agricultural products. Its potential biological activity may be harnessed to develop innovative solutions for crop protection and enhancement.
Used in Materials Science:
N-(3,5-Dibromo-2-pyridyl)thiourea, 97% is utilized in materials science for the development of new materials with specific properties. Its chemical structure can be manipulated to create materials with tailored characteristics for various applications.

Upstream product

• 35486-42-1 2-amino-3,5-dibromopyridine 
• 115-08-2 thiocarboxamide 
• 31430-58-7 N-[(3,5-dibromopyridin-2-yl)carbamothioyl]benzamide 

Downstream Products

• 960535-44-8 6-bromo-2-chlorothiazolo[4,5-b]pyridine 
• 857970-06-0 2-amino-6-bromo[1,3]thiazolo[4,5-b]pyridine 
• 1264193-12-5 6-bromo[1,3]thiazolo[4,5-b]pyridine 
• 2104019-86-3 methylthiazolo[4,5-b]pyridine-6-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Chemical synthesis method of thiazolo[4,5-b]pyridyl-6-carboxylic acid

The invention relates to a chemical synthesis method of thiazolo[4,5-b]pyridyl-6-carboxylic acid. According to the method, starting from 3,5-dibromo-2-aminopyridine as a raw material, five steps of reactions comprising an acylation reaction, a cyclization reaction, a diazotization reaction, a carbonyl insertion reaction and a hydrolysis reaction are carried out to synthesize the thiazolo[4,5-b]pyridyl-6-carboxylic acid. An efficient synthesis method is provided for synthesis of the compound.

ACETIC ACID AMIDE DERIVATIVE HAVING INHIBITORY ACTIVITY ON VASCULAR ENDOTHELIAL LIPASE

Disclosed is a compound which is useful as an endothelial lipase inhibitor. A pharmaceutical composition having inhibitory activity on endothelial lipase comprising a compound represented by the formula: , its pharmaceutically acceptable salt, or a solvate thereof, wherein Ring A is nitrogen-containing hetero ring, Ring A may be substituted with a substituent other than a group represented by the formula: -C(R1R2)-C(=O)-NR3R4 and a group represented by the formula: -R5, a broken line represents the presence or the absence of a bond, Z is -NR6-, =N-, -O-, or -S-, R6 is halogen, substituted or unsubstituted alkyl or the like, R1 and R2 are each independently hydrogen, halogen, hydroxy, cyano, nitro, carboxy or substituted or unsubstituted alkyl, R3 is hydrogen or substituted or unsubstituted alkyl, R4 is hydrogen, substituted or unsubstituted alkyl or the like, R3 and R4 taken together with the adjacent nitrogen atom to which they are attached may form a substituted or unsubstituted ring, R5 is hydrogen, halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl or the like.