315660-07-2Relevant academic research and scientific papers
Synthesis of tritium labeled (±)-1-[2-(triphenylmethoxy)ethyl]-3-piperidinecarboxylic acid: A possible compound to determine the efficacy of potential GABA transporter substances in vitro
Schirrmacher, Ralf,Hamkens, Wilhelm,Lueddens, Hartmut,Roesch, Frank
, p. 1127 - 1134 (2000)
(±)- 1-[2-(Triphenyl[3H]methoxy)ethyl]-3-piperidinecarboxylic acid ([3H]SNAP-5114) with a specific activity of 40 Ci/mmol was prepared in a two step synthesis starting from ethyl (2-(4-hydroxyphenyl)bis(4-methoxyphenyl)methoxy)-ethyl)piperidine-3-carboxyla te and [3H]methyliodide with subsequent hydrolysis of the resulting ester with lithium hydroxide to yield the desired [3H]SNAP-5114. (C) 2000 John Wiley and Sons, Ltd.
