315717-77-2

Basic information

• Product Name: 3-AMINOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER
• Synonyms: 3-(AMINOMETHYL)-1-CBZ-PYRROLIDINE;3-AMINOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER;N-Cbz-3-(aminomethyl)pyrrolidine
• CAS NO: 315717-77-2
• Molecular Formula: C₁₃H₁₈N₂O₂
• Molecular Weight: 234.29
• Mol File: 315717-77-2.mol

Chemical Properties

• Boiling Point: 370.5 °C at 760 mmHg
• Flash Point: 177.9 °C
• Appearance: /
• Density: 1.155
• Vapor Pressure: 1.1E-05mmHg at 25°C
• Refractive Index: 1.56
• Storage Temp.: 2-8°C
• PKA: 10.12±0.29(Predicted)
• CAS DataBase Reference: 3-AMINOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER(315717-77-2)
• EPA Substance Registry System: 3-AMINOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER(315717-77-2)

Safety Data

• Hazardous Substances Data: 315717-77-2(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
3-AMINOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER is used as a building block for the synthesis of various organic molecules. Its unique structure allows for the creation of a wide range of compounds with diverse properties and applications.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 3-AMINOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER is used as a starting material for the development of new pharmaceuticals. The presence of the aminomethyl and carboxylic acid groups in this compound makes it a promising candidate for the synthesis of biologically active compounds with potential therapeutic applications.
Used as a Reagent:
3-AMINOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER is also utilized as a reagent in the preparation of various biologically active compounds. Its versatility and reactivity make it a valuable tool in the synthesis of complex organic molecules and pharmaceutical agents.

InChI:InChI=1/C13H18N2O2/c14-8-12-6-7-15(9-12)13(16)17-10-11-4-2-1-3-5-11/h1-5,12H,6-10,14H2/t12-/m0/s1

Upstream product

• 604798-64-3 (3R,4S)-3-azidomethyl-1-benzyloxycarbonyl-4-hydroxypyrrolidine 
• 124-63-0 methanesulfonyl chloride 
• 315718-05-9 benzyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate 

Downstream Products

• 455266-19-0 3-[(9H-Purin-6-ylamino)-methyl]-pyrrolidine-1-carboxylic acid benzyl ester 
• 455266-17-8 3-(Pteridin-4-ylaminomethyl)-pyrrolidine-1-carboxylic acid benzyl ester 
• 471250-43-8 (R,S) 3-[(4-hydroxy-benzoylamino)-methyl]-pyrrolidine-1-carboxylic acid benzyl ester 

Relevant articles and documents

Synthesis and antibacterial activity of novel pyrido[1,2,3-de][1,4] benzoxazine-6-carboxylic acid derivatives carrying the 3-cyclopropylaminomethyl- 4-substituted-1-pyrrolidinyl group as a C-10 substituent

Novel pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid derivatives 5-9 carrying a 3-cyclopropylami-nomethyl-4-substituted-1-pyrrolidinyl moiety at the C-10 position were synthesized and their in vitro antibacterial activity, intravenous single-dose toxi

N-substituted nonaryl-heterocyclo amidyl NMDA/NR2B Antagonists

Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are effective as NMDA NR2B antagonists useful for relieving pain.

N-substituted nonaryl-heterocyclic NMDA/NR2B antagonists

Compounds represented by Formula (I): 1or pharmaceutically acceptable salts thereof, are effective as NMDA NR2B antagonists useful for relieving pain.

SRC kinase inhibitor compounds

Pyrimidine compounds (Formula I), or their pharmaceutically acceptable salts, hydrates, solvates, crystal forms and individual diastereomers, and pharmaceutical compositions including the same, which are inhibitors of tyrosine kinase enzymes, and as such are useful in the prophylaxis and treatment of proteins tyrosine kinase-associated disorders, such as immune diseases, hyperproliferative disorders and other diseases in which inappropriate protein kinase action is believed to play a role, such as cancer, angiogensis, atheroscelerosis, graft rejection, rheumatoid arthritis and psoriasis.