31576-84-8Relevant academic research and scientific papers
4-Phenyl quinoline derivatives as potential serotonin receptor ligands with antiproliferative activity
Joshi, Pranaya V.,Sayed, Alim A.,RaviKumar, Ameeta,Puranik, Vedavati G.,Zinjarde, Smita S.
, p. 246 - 258 (2017/05/12)
Antagonists of signaling receptors are often effective non-toxic therapeutic agents. Over the years, there have been evidences describing the role of serotonin or 5-hydroxytryptamine (5-HT) in development of cancer. Although there are reports on the antip
v-Triazolines. Part 37. Rearrangement reactions of 5-amino-1-(2-formyl-, -benzoyl-, -cyano-aryl)-v-triazolines: New synthesis of 2-amino- and 2,4-diamino-quinolines and 2,4-diamino-1,7-naphthyridines
Beccalli, Egle M.,Erba, Emanuela,Gelmi, Maria Luisa,Pocar, Donato
, p. 1359 - 1364 (2007/10/03)
2-Aminoquinolines 4 were obtained in an one-pot reaction from arylacetaldehydes 1, secondary amines 2 and aryl azides 3 in refluxing benzene or xylene. 2,4-Diaminoquinolines and 2,4-diamino-1,7-naphthyridines 9 were prepared by heating arylacetaldehydes 1 with secondary amines 2 and aryl or pyridyl azides 8 and reaction with bases. Reaction intermediates were shown in certain cases to be 5-amino-v-triazolines 5 and 10 undergoing thermal rearrangement to amidines 7 and 11 followed by intramolecular base-catalysed cyclocondensation.
An efficient synthesis of 4-phenyl-2-aminoquinolines
Sayed
, p. 749 - 756 (2007/10/02)
An efficient procedure for 3-substituted-4-Phenyl-2-aminoquinolines involving the reaction between a preformed complex of amide 2 and phosphorus oxychloride with o-acetamidobenzophenone is reported. Hitherto unknown ten 4-Phenyl-2-aminoquinolines have bee
