3159-00-0

Upstream product

• 719-59-5 5-chloro-2-aminobenzophenone 
• 106-47-8 4-chloro-aniline 
• 536-74-3 phenylacetylene 
• 3158-98-3 1-(2-amino-5-chlorophenyl)-1-phenylethan-1-ol 

Downstream Products

• 858621-43-9 7-acetyl-3-chloro-8-iodomethyl-8-phenylbicyclo[4.2.0]-7-azaocta-1,3,5-triene 

Relevant academic research and scientific papers

Palladium(ii)-catalyzed vinylic geminal double C-H activation and alkyne annulation reaction: Synthesis of pentafulvenes

The first transition-metal-catalyzed vinylic geminal double C(sp2)-H activation and di-substituted alkyne annulation reaction is reported. This palladium(ii)-catalyzed, amide directed reaction of vinylic compounds with di-substituted alkynes offers an efficient synthetic path to pentafulvenes, which are very important compounds because of their bioactivity and interesting optical properties. A FeCl3-mediated transformation of pentafulvenes to fluorescent cyclopenta[b]quinolines is also developed.

Synthesis of benzazetine derivatives by intramolecular iodoamination of o-(acylamino)styrene derivatives

The iodoamination of o-(acylamino)styrene derivatives using iodine and sodium hydrogencarbonate, producing 7-acyl-8-iodomethylbicyclo[4.2.0]-7-azaoct- 1,3,5-triene [1-acyl-2-(iodomethyl)benzazetine] derivatives, is described. Replacement of the iodo moiety by hydrogen or phenylthio group is also reported.