3163-15-3Relevant articles and documents
One-pot synthesis of hydroxybenzo[d]- oxazole-2-aliphatic acid derivatives by Meerwein's reagent
Zhang, Wei,Liu, Wenlu,Jiang, Xizhen,Jiang, Faqin,Fu, Lei
, p. 2772 - 2779 (2012)
(Chemical Equation Presented) A general one-pot synthesis of hydroxylbenzo[d]oxazole-2-aliphatic acid esters and hydroxylbenzo[d]oxazole-2- amino acid esters was successfully achieved in good yield by using Meerwein's reagent. Copyright Taylor & Francis G
Ether compound and pharmaceutical application thereof in prevention and treatment of diabetes and metabolic syndrome
-
Paragraph 0250-0251; 0363-0365, (2021/07/24)
The invention relates to an ether compound and a pharmaceutical application thereof in prevention and treatment of diabetes and metabolic syndrome. Specifically, the invention provides a compound as shown in a formula (I), an isomer, a raceme, a prodrug, a solvate, a deuterated substance or a pharmaceutically acceptable salt thereof, and Ar1, Ar2, X, Y and R are defined in the specification.
PRMT5 INHIBITORS AND USES THEREOF
-
Paragraph 0432-0433, (2019/04/05)
Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.