31675-37-3

Upstream product

• 611-15-4 1-methyl-2-vinyl-benzene 
• 108-24-7 acetic anhydride 
• 529-20-4 2-methylphenyl aldehyde 

Downstream Products

• 430452-86-1 ethyl 6-methyl-2-thioxo-4-(o-tolyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate 
• 418803-02-8 ethyl 6-methyl-4-(2-methylphenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 
• 1273320-74-3 C₁₈H₁₇BrS₂ 
• 1273320-75-4 C₂₄H₁₇BrS₂ 
• 243-42-5 β-brazan 
• 243-46-9 benzo[b]naphtho[2,3-d]thiophene 
• 37803-24-0 o-Diacetoxymethyl-benzylbromid 
• 2319-96-2 5-methyltetraphene 
• 148875-99-4 2-Acetoxymethyl-benzyliden-diacetat 
• 60633-91-2 2-(bromomethyl)benzaldehyde 
• 529-20-4 2-methylphenyl aldehyde 
• 17373-93-2 2-methylbenzyl acetate 

Relevant academic research and scientific papers

One-pot synthesis of 1H-isochromenes and 1,2-dihydroisoquinolines by a sequential isocyanide-based multicomponent/Wittig reaction

A one-pot synthesis of 1H-isochromenes and 1,2-dihydroisoquinolines by a I-MCR/Wittig sequence was developed. The reaction of phosphonium salt 5, an acid, an amine (or without), and an isocyanide gave the 1H-isochromenes 7 or 1,2-dihydroisoquinolines 9 in

Theoretical investigation on the crystal structure, spectral and optical properties of a novel organic optical material: (Acetoxy) (2-methylphenyl) methylacetate

An organic material (Acetoxy)(2-methylphenyl) methyl acetate (AMPMA) was synthesized at temperature and its chemical structure was analyzed by vibrational spectroscopic studies (FT-IR/FT-Raman) and NMR spectroscopy. HF and DFT/B3LYP theoretical methods were employed on AMPMA to investigate its molecular geometry, vibrational and bonding nature. The time-dependent HOMO-LUMO energy was found to be 6.0260 eV. The optical properties of the material were discussed through dipole moment and optical polarization. In this contest, the estimation of molecular dipole moment (μ) and linear polarizability (α) were studied by MP2, DFT and HF methods with different basis sets.

Zinc zirconium phosphate as an efficient catalyst for chemoselective synthesis of 1,1-diacetates under solvent-free conditions

In the present study, a mild, rapid, and efficient method for the protection of aldehydes with acetic anhydride (AA) in the presence of zinc zirconium phosphate (ZPZn) as a nano catalyst, at room temperature is reported. Selective conversion of aldehydes was observed in the presence of ketones. Under these conditions, different aldehydes bearing electron-withdrawing and electron-donating substituents were reacted with AA and the corresponding 1,1-diacetates (acylals) were obtained in high to excellent yields. The steric and electronic properties of the different substrates had a significant influence on the reaction conditions. Also, the deprotection of 1,1-diacetates has been achieved using this catalyst in water. This nanocatalyst was characterized by several physico-chemical techniques. It was recovered easily from the reaction mixture, regenerated and reused at least 7 times without significant loss in catalytic activity. This protocol has the advantages of easy availability, stability, reusability of the eco-friendliness, chemoselectivity, simple experimental and work-up procedure, solvent-free conditions and usage of only a stoichiometric amount of AA.

Poly(4-vinylpyridinium) perchlorate as an efficient solid acid catalyst for the chemoselective preparation of 1,1-diacetates from aldehydes under solvent-free conditions

Poly(4-vinylpyridinium) perchlorate has been used as a supported, recyclable, environmentally-benign catalyst for the formation of acylals from aliphatic and aromatic aldehydes in good to excellent yields under solvent-free conditions. Notably, the reaction conditions were tolerant of ketones. This methodology offers several distinct advantages, including its operational simplicity and high product yield, as well as being green in terms of avoiding the use of toxic catalysts and solvents. Furthermore, the catalyst can be recovered and reused several times without any loss in its activity.

Sulfonated rice husk ash (RHA-SO3H): A highly powerful and efficient solid acid catalyst for the chemoselective preparation and deprotection of 1,1-diacetates

Rice husk ash (RHA), as a source of amorphous silica, was treated with chlorosulfonic acid and sulfonated rice husk ash (RHA-SO3H) as a highly powerful solid acid catalyst was obtained and characterized with a variety of techniques including IR, TGA, SEM, XRD, pH analysis, Hammett acidity function and BET method. This solid acid showed excellent catalytic activity for the protection and deprotection of aldehydes with Ac2O at room temperature under solvent free conditions. The procedure gave the products in excellent yields in very short reaction times and good to high yields. Also this catalyst can be reused for several times without loss of its catalytic activity.

Ultrasound assisted the chemoselective 1,1-diacetate protection and deprotection of aldehydes catalyzed by poly(4-vinylpyridinium)hydrogen sulfate salt as a eco-benign, efficient and reusable solid acid catalyst

Poly(4-vinylpyridinium) hydrogen sulfate solid acid was found to be efficient catalyst for preparation of 1,1-diacetate using ultrasound irradiation at ambient temperature and neat condition. Deprotection of the resulting 1,1-diacetates were achieved using the same catalyst in methanol solvent under ultrasound irradiation at room temperature. This new method consistently has the advantage of excellent yields and short reaction times. Utilization of solvent free, simple reaction conditions, isolation, and purification makes this manipulation very interesting from an economic and environmental perspective. Further, the catalyst can be reused and recovered for several times.

A succinimide-N-sulfonic acid catalyst for acetylation reactions in absence of a solvent

A small amount of succinimide-N-sulfonic acid efficiently catalyzed the acetylation of a variety alcohols, phenols, thiols, amines and aldehydes with acetic anhydride at room temperature under solvent free conditions. This catalyst has the advantages of excellent yields and short reaction times and the reaction can be carried out on a large scale, which makes it potentially useful for industrial applications.

Rice husk supported FeCl3 nanoparticles as an efficient and reusable catalyst for the chemoselective 1,1-diacetate protection and deprotection of aldehydes

1,1-Diacetates were produced from a variety of aromatic aldehydes using rice husk supported FeCl3 nanoparticles as a catalyst. The procedure generally resulted in good yields (98%) of aromatic aldehydes including those carrying electron donating- or withdrawing-substituents. Deprotection of the resulting 1,1-diacetates was also achieved using the same catalyst in ethanol. This new method consistently has the advantages of excellent yields and relatively short reaction times. Further, the catalyst can be reused and recovered for several times.

Introduction of N-sulfonic acid poly(4-vinylpyridinum) chloride as an efficient and reusable catalyst for the chemoselective 1,1-diacetate protection and deprotection of aldehydes

N-sulfonic acid poly(4-vinylpyridinium) chloride is easily prepared by the reaction of poly(4-vinylpyridine) with neat chlorosulfonic acid. This reagent can be used as an efficient catalyst for the preparation of 1,1-diacetates at room temperature and neat condition. Deprotection of the resulting 1,1-diacetates can also be achieved using the same catalyst in methanol. This new method consistently has the advantages of excellent yields and short reaction times. Further, the catalyst can be reused and recovered for several times.

A highly efficient solvent-free acetalization of aldehydes to 1,1-diacetates catalyzed by SiO2-Pr-SO3H

1,1-Diacetates are prepared in excellent yields from aldehydes and acetic anhydride under solvent-free conditions at room temperature in short reaction times using catalytic amount of sulfonic acid functionalized silica (SiO 2-Pr-SO3H) which could be easily handled and removed from the mixture of reaction.