37803-24-0Relevant academic research and scientific papers
One-pot synthesis of 1H-isochromenes and 1,2-dihydroisoquinolines by a sequential isocyanide-based multicomponent/Wittig reaction
Wang, Long,Guan, Zhi-Rong,Ding, Ming-Wu
, p. 2413 - 2420 (2016/03/01)
A one-pot synthesis of 1H-isochromenes and 1,2-dihydroisoquinolines by a I-MCR/Wittig sequence was developed. The reaction of phosphonium salt 5, an acid, an amine (or without), and an isocyanide gave the 1H-isochromenes 7 or 1,2-dihydroisoquinolines 9 in
Lewis acid mediated one-pot synthesis of aryl/heteroaryl-fused carbazoles involving a cascade Friedel-Crafts alkylation/electrocyclization/aromatization reaction sequence
Sureshbabu, Radhakrishnan,Saravanan, Velu,Dhayalan, Vasudevan,Mohanakrishnan, Arasambattu K.
experimental part, p. 922 - 935 (2011/04/22)
A Lewis-acid-mediated domino reaction of 2/3-(bromomethyl)indoles with arenes/heteroarenes led to the formation of the corresponding annulated carbazoles. This three-step one-pot transformation proceeds by sequential Lewis acid catalysed Friedel-Crafts alkylation, electrocyclization and aromatization reactions. The strategy is highly efficient for the assembly of complex aryl/heteroaryl-fused carbazoles.
