31719-05-8

Basic information

• Product Name: N,N'-DIBENZYLBUTANE-1,4-DIAMINE
• Synonyms: N,N'-DIBENZYLBUTANE-1,4-DIAMINE
• CAS NO: 31719-05-8
• Molecular Formula: C₁₈H₂₄N₂
• Molecular Weight: 268.4
• Mol File: 31719-05-8.mol

Chemical Properties

• Melting Point: 65 °C
• Boiling Point: 401.5 °C at 760 mmHg
• Flash Point: 235.7 °C
• Appearance: /
• Density: 1.006 g/cm³
• PKA: 9.95±0.19(Predicted)
• CAS DataBase Reference: N,N'-DIBENZYLBUTANE-1,4-DIAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-DIBENZYLBUTANE-1,4-DIAMINE(31719-05-8)
• EPA Substance Registry System: N,N'-DIBENZYLBUTANE-1,4-DIAMINE(31719-05-8)

Safety Data

• Hazardous Substances Data: 31719-05-8(Hazardous Substances Data)

Usage

Uses

Used in Adhesive and Coating Formulations:
N,N'-Dibenzylbutane-1,4-diamine is used as a curing agent for epoxy resins in adhesive and coating formulations, improving their mechanical and thermal properties, which results in more durable and heat-resistant products.
Used in Composite Material Manufacturing:
In the manufacturing of composite materials, N,N'-Dibenzylbutane-1,4-diamine serves as a curing agent for epoxy resins, contributing to the production of stronger and more heat-resistant composites.
Used in General Industrial Applications:
N,N'-Dibenzylbutane-1,4-diamine is utilized across various industries as a curing agent for epoxy resins, enhancing their performance characteristics for a range of applications, including but not limited to electronics, automotive, and construction sectors.
It is crucial to handle N,N'-dibenzylbutane-1,4-diamine with caution due to its potential to cause irritation to the skin, eyes, and respiratory system. Proper safety measures should be taken during its use to mitigate any adverse effects.

Upstream product

• 31991-78-3 uvariadiamide 
• 6970-47-4 N,N-bis-(phenylmethylene)butane-1,4-diamine 
• 100-52-7 benzaldehyde 
• 110-60-1 1,4-diaminobutane 
• 6970-47-4 N¹,N²-dibenzylidenebutane-1,4-diamine 

Downstream Products

• 1004318-32-4 C₂₃H₂₇N₃O₂S 
• 352709-99-0 N,N'-bis-(cholesteryloxycarbonylmethyl)-N,N'-dibenzyl-1,4-diaminobutane 
• 1597437-53-0 N-benzyl-N′-benzylidene-1,4-diaminobutane 
• 110-60-1 1,4-diaminobutane 
• 87142-91-4 N-benzylidene-1,4-diaminobutane 
• 29867-04-7 N-(4-aminobutyl)(phenylmethyl)amine 
• 29867-15-0 N,N'-(butane-1,4-diyl)bis(N-benzylethanamide) 
• 1311508-42-5 C₂₆H₃₂N₂O₆ 
• 1360761-60-9 (Z)-methyl 2-(3-benzoyl-4,9-dimethyl-2-oxo-10a-phenyl-4,5,6,7,8,9-hexahydro-2H-furo[3,2-b][1,5]diazonin-10(10aH)-ylidene)acetate 
• 1225561-89-6 1,3-dibenzyl-1,3-diazepan-2-one 
• 107886-60-2 C₅₁H₅₇N₅O₄ 
• 107886-64-6 C₅₁H₅₇N₅O₄ 
• 177798-00-4 Acetic acid (R)-1-[({4-[((R)-2-acetoxy-4-acetylamino-butyl)-benzyl-amino]-butyl}-benzyl-amino)-methyl]-3-acetylamino-propyl ester 

Relevant articles and documents

METHODS FOR PRODUCING (6S,15S)-3,8,13,18-TETRAAZAICOSANE-6,15-DIOL

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A minimalistic approach to develop new anti-apicomplexa polyamines analogs

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Synthesis and investigation of new cyclic haloamidinium salts

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Synthesis and evaluation of hexahydropyrimidines and diamines as novel hepatitis C virus inhibitors

In order to identify novel anti-hepatitis C virus (HCV) agents we devised cell-based strategies and screened phenotypically small molecule chemical libraries with infectious HCV particles, and identified a hit compound (1) containing a hexahydropyrimidine (HHP) core. During our cell-based SAR study, we observed a conversion of HHP 1 into a linear diamine (6), which is the active component in inhibiting HCV and exhibited comparable antiviral activity to the cyclic HHP 1. In addition, we engaged into the biological characterization of HHP and demonstrated that HHP does not interfere with HCV RNA replication, but with entry and release of viral particles. Here we report the results of the preliminary SAR and mechanism of action studies with HHP.

Synthesis and antikinetoplastid activity of a series of N,N×-substituted diamines

A series of 25 N,N×-substituted diamines were prepared by controlled reductive amination of free aliphatic diamines with different substituted benzaldehydes. The library was screened in vitro for antiparasitic activity on the causative agents of human Afr

Design, synthesis and biological activity of peptidomimetic analogs of insect allatostatins

Allatostatins (ASTs) comprise a family of insect neuropeptides isolated from cockroaches and found to inhibit the production of juvenile hormone (JH) by the corpora allata (CA). For this reason, the ASTs can be regarded as possible IGR candidates for pest control. Six peptidomimetic analogs according to the C-terminal pentapeptide of ASTs were prepared by solid-phase organic synthetic methods in an attempt to obtain new simple substitution agents. Assays of inhibition of JH biosynthesis in vitro by corpora allata from the cockroach Diploptera punctata showed that the activity of analog I (IC50: 0.09 μM) was more active than that of the C-terminal pentapeptide (Tyr-Xaa-Phe-Gly-Leu-NH2, IC50: 0.13 μM) it mimicked and the activity of the analog II (IC50: 0.13 μM) proved roughly equivalent to the C-terminal pentapeptide. The results indicate that a new simple mimicry for Tyr-Xaa-Phe-Gly has been discovered; analog I may be a novel compound candidate for potential IGRs. This study will be useful for the design of new AST analogs for insect management.

MODULATORS OF PHARMACOKINETIC PROPERTIES OF THERAPEUTICS

The present application provides for a compound of Formula I, or a pharmaceutically acceptable salt, solvate, and/or ester thereof, compositions containing such compounds, therapeutic methods that include the administration of such compounds, and therapeutic methods and include the administration of such compounds with at least one additional therapeutic agent.

Double dearomatization of bis(diphenviphosphinamides) through anionic cyclization. A facile route of accessing multifunctional systems with antitumor properties

(Chemical Equation Presented) The sequential one-pot double dearomatization of bis(N-benzyl-P,P-diphenylphosphinamides) via anionic cyclization is described for the first time. Protonation and alkylation of the dearomatized dianions provide bis(tetrahydro

Syntheses of a Series of Linear Pentaamines with Three and Four Methylene Chain Intervals

Ten kinds of linear pentaamines with various combinations of 3 or 4 methylene chain intervals were synthesized.The methods were tentatively classified into two, leading to symmetrical and unsymmetrical pentaamines, all of which were prepared by succesive alkylation of secondary amino derivatives of benzylamine with N-(3-bromopropyl or 4-bromobutyl)phthalimide in the presence of KF-Celite, coupled with the purification of the phthaloyl compounds by silica gel column chromatography.Protecting benzyl and phthaloyl groups were removed by usual methods.The carbon-13 nuclear magnetic resonance (13C-NMR) spectra ot the ten pentaamines were recorded in D2O as fully protonated forms, and a comparative analysis of their spectra allowed the complete assignment of all 13C chemical shifts.Keywords-polyamine; pentaamine; benzylamine; N-(3-bromopropyl)phthalimide; N-(4-bromobutyl)phthalimide; alkylation; potassium fluoride-Celite; 13C-NMR spectrum