31729-99-4

Upstream product

• 67-56-1 methanol 
• 135908-69-9 (7S,8S)-2,2-Dimethyl-8-phenyl-5-oxa-2-sila-bicyclo[5.3.1]undec-1⁽¹⁰⁾-en-6-one 
• 2857-97-8 trimethylsilyl bromide 
• 20378-60-3 trans-6-phenyl-3-cyclohexene-1-carboxylic acid 
• 124-41-4 sodium methylate 
• 140-10-3 (E)-3-phenylacrylic acid 

Relevant academic research and scientific papers

AMINO-PYRIMIDONYL DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Compounds of formula (I), wherein R1, R2, R3, R4, R5, R6, J and n are as defined in the description. Medicaments.

NEW PIPERIDINYL DERIVATIVES AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7

Compounds of formula (I): wherein R1, R2, R3, B, W, Z, m and n are as defined in the description The compounds of the present invention have pro-apoptotic and/ or anti-proliferative properties making it possible to use the

Pericyclic Umpolung. Reversal of Regioselectivity in the Diels-Alder Reaction

New methodology is reported which enables reversal of regiochemistry in the Diels-Alder reaction.Esterification of 2-(β-hydroxyethyl)dimethylsilyldienes with common dienophiles followed by type 2 intramolecular Diely-Alder reaction results in formation of a single regio- and stereoisomer.Oxidative cleavage of the cycloadduct produces a cyclohexanone with a substitution pattern opposite of that found in the analogous bimolecular cycloaddition reaction.