317318-98-2

Upstream product

• 609-15-4 ethyl 2-chloro-3-oxo-butyrate 
• 455-24-3 4-trifluoromethylbenzoic acid 

Downstream Products

• 933772-45-3 4-bromomethyl-2-(4-trifluoromethyl-phenyl)-oxazole-5-carboxylic acid ethyl ester 
• 317318-99-3 5-chloromethyl-4-methyl-2-(4-trifluoromethylphenyl)-oxazole 
• 109544-12-9 [4-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-5-yl]-methanol 

Relevant academic research and scientific papers

A new approach to the synthesis of 2-aryl-4-halomethyl-5-methyl-1,3- oxazoles by highly regioselective direct halogenation with NBS or NCS/MeCN

A simple and efficient method for the synthesis of 2-aryl-4-bromomethyl-5- methyl-1,3-oxazoles 2 and 2-aryl-4-chloromethyl-5-methyl-1,3-oxazoles 3 is described. The reaction of 2-aryl-4,5-dimethyl-1,3-oxazoles 1 with N-bromosuccinimide and N-chlorosuccini