317334-60-4

Usage

Physical Form

White to off-white crystalline powder

Application

Used in the synthesis of pharmaceuticals and fine chemicals

Properties

Antimicrobial and Antiviral: Exhibits antimicrobial and antiviral properties
Starting Material: Commonly utilized as a starting material in the production of active pharmaceutical ingredients
Building Block: Acts as a building block in the synthesis of organic compounds
Reagent: Employed as a reagent in organic chemical reactions

Safety

Requires careful handling and storage due to potential health and environmental hazards

Upstream product

• 626-39-1 1,3,5-trisbromobenzene 
• 100-52-7 benzaldehyde 
• 51339-31-2 3,5-dibromo-benzhydrol 
• 71572-36-6 3-benzyl-1,5-dibromobenzene 

Downstream Products

• 251966-71-9 (3-benzyl-5-bromo)benzyl bromide 
• 500732-66-1 2-(3-benzyl-5-bromo-benzyl)-isothiazolidine 1,1-dioxide 
• 317335-30-1 1-[3-benzyl-5-(1,1-dioxo-isothiazolidin-2-ylmethyl)-phenyl]-ethanone 
• 422550-94-5 1-[3-benzyl-5-(1,1-dioxoisothiazolidin-2-ylmethyl)-phenyl]-1-(8-hydroxy-[1,6]naphthyridin-7-yl)-methanone 
• 1026627-33-7 {2-[3-benzyl-5-(1,1-dioxo-isothiazolidin-2-ylmethyl)-phenyl]-2-oxo-ethyl}-(2-chloro-pyridin-3-ylmethyl)-carbamic acid benzyl ester 
• 422550-95-6 3-[({2-[3-benzyl-5-(1,1-dioxo-isothiazolidin-2-ylmethyl)-phenyl]-2-oxo-ethyl}-benzyloxycarbonyl-amino)-methyl]-pyridine-2-carboxylic acid ethyl ester 
• 317333-21-4 1-(3-benzyl-5-[1,2,4]triazol-1-ylmethylphenyl)-3-(4-methylpyridin-2-yl)-propane-1,3-dione 
• 317332-80-2 1-[3-benzyl-5-(2-oxo-2H-pyridin-1-ylmethyl)phenyl]-3-(4-methylpyridin-2-yl)-propane-1,3-dione 
• 317334-94-4 3-benzyl-5-[1,2,4]triazol-1-ylmethylacetophenone 
• 317334-62-6 3-benzyl-5-(2-oxo-2H-pyridin-1-ylmethyl)acetophenone 

Relevant academic research and scientific papers

Design and synthesis of 8-hydroxy-[1,6]naphthyridines as novel inhibitors of HIV-1 integrase in vitro and in infected cells

Naphthyridine 7 inhibits the strand transfer of the integration process catalyzed by integrase with an IC50 of 10 nM and inhibits 95% of the spread of HIV-1 infection in cell culture at 0.39 μM. It does not exhibit cytotoxicity in cell culture

1-(Aromatic- or heteroaromatic-substituted)-3-(heteroaromatic substituted)-1,3-propanediones and uses thereof

Certain 1-(aromatic- or heteroaromatic-substituted-3-(heteroaromatic substituted)-1,3-propanediones are described as inhibitors of HIV integrase and inhibitors of HIV replication. These compounds are useful in the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.