31736-73-9

Usage

Uses

Used in Chemical Synthesis:
4'-BROMO-3-CHLOROPROPIOPHENONE is used as an intermediate in the synthesis of various organic compounds for [application reason]. Its unique halogenated structure allows for further functionalization and incorporation into a wide range of chemical products.
Used in Pharmaceutical Industry:
4'-BROMO-3-CHLOROPROPIOPHENONE is used as a building block for the development of new pharmaceutical compounds for [application reason]. Its structural properties make it a valuable candidate for the creation of novel drugs with potential therapeutic applications.
Used in Research and Development:
4'-BROMO-3-CHLOROPROPIOPHENONE is used as a research compound for [application reason] in academic and industrial laboratories. Its unique properties and reactivity make it an important tool for studying various chemical reactions and processes.
Used in Material Science:
4'-BROMO-3-CHLOROPROPIOPHENONE is used as a component in the development of new materials for [application reason], such as in the creation of advanced polymers or other specialized materials with unique properties.

Flammability and Explosibility

Notclassified

Upstream product

• 108-86-1 bromobenzene 
• 625-36-5 2-chloropropionyl chloride 
• 161386-38-5 5-[5-fluoro-3-(4-methoxytetrahydropyran-4-yl)phenylthio]indan-1-one 
• 51044-13-4 4-bromobenzyl triphenylphosphonium bromide 
• 109240-30-4 1-(4-bromophenyl)cyclopropan-1-ol 
• 106-37-6 1.4-dibromobenzene 

Downstream Products

• 97802-13-6 4-p-biphenylyl-7-p-bromophenyl-1,10-phenanthroline 
• 97802-09-0 4-p-bromophenyl-8-nitroquinoline 
• 16324-12-2 [3-(4-Bromo-phenyl)-3-oxo-propyl]-phosphonic acid diethyl ester 
• 34598-49-7 5-Bromo-1-indanone 
• 22731-70-0 1-(4-bromophenyl)prop-2-en-1-one 
• 97802-08-9 4,7-bis-(p-bromophenyl)-1,10-phenanthroline 
• 97802-07-8 4-p-bromophenyl-1,10-phenanthroline 

Relevant academic research and scientific papers

I2-Promoted Intramolecular Oxidative Cyclization of Butenyl Anilines: A Facile Route to Benzo[b]azepines

A metal-free approach for the synthesis of seven-membered N-heterocycles has been developed by the I2-promoted intramolecular cross-coupling/annulation of butenyl anilines. This cyclization reaction involves C?H activation and C?C bond formation and exhibits good functional group tolerance. A series of benzo[b]azepine derivatives are obtained in moderate to good yields.

How an early or late transition state impacts the stereoselectivity of tetrahydropyran formation by intramolecular oxa-Michael addition

The intramolecular oxa-Michael addition giving tetrahydropyrans has been examined experimentally using both acidic and basic catalysis. With acidic catalysis, the diequatorial product is exclusively obtained in a kinetically controlled reaction in all cas

NEW COMPOUNDS SUITABLE AS CATALYSTS FOR POLYMERIZATION REACTIONS

The invention relates to a compound of formula (I) and a process for synthesizing said compound. The invention further relates to the use of said compound as a catalyst, preferably for polymerization, such as, olefin polymerization. The invention also relates to the polymers produced using said catalyst and articles comprising said polymers.

Highly enantioselective [3+2] coupling of cyclic enamides with quinone monoimines promoted by a chiral phosphoric acid

Enantioselective [3+2] coupling of cyclic enamides with quinone monoimines was realised using a chiral phosphoric acid as a catalyst. This transformation allowed for the synthesis of highly enantioenriched polycyclic 2,3-dihydrobenzofurans (up to 99.9% ee). The absolute configuration of one product was determined by an X-ray crystal structural analysis. We also found a possible mechanism for this reaction.

Regioselective Synthesis of Carbonyl-Containing Alkyl Chlorides via Silver-Catalyzed Ring-Opening Chlorination of Cycloalkanols

A novel and regioselective approach to carbonyl-containing alkyl chlorides via silver-catalyzed ring-opening chlorination of cycloalkanols is reported. Concurrent C(sp3)-C(sp3) bond cleavage and C(sp3)-Cl bond formation efficiently occur with good yields under mild conditions, and the chlorinated products are readily transformed into other useful synthetic intermediates and drugs. The reaction features complete regioselectivity, high efficiency, and excellent practicality. (Chemical Equation Presented).

Properties and structure of two fluorinated 1,10-phenanthrolines

We report the synthesis, X-ray structure, absorbance and emission of 4,7-bis(4-fluorophenyl)-1,10-phenanthroline and 4,7-bis-(4′-trifluoromethyl-biphenyl-4-yl)-1,10-phenanthroline. 4,7-Bis(4-fluorophenyl)-1,10-phenanthroline was synthesized by successive Skraup reactions and features absorbance at 274 nm and emission at 384 nm while 4,7-bis-(4′-trifluoromethyl-biphenyl-4-yl)-1,10-phenanthroline featured absorbance at 283 nm and emission at 400 nm. The structures show molecular stacking of the phenyl groups and phenanthroline structure and longitudinal fluorine atom associations within the crystal lattice. Furthermore, the three fused rings of the 4,7-bis(4-fluorophenyl)-1,10-phenanthroline unit exhibited torsion up to 13.97(9)° throughout the crystal lattice whereas no torsion is observed for 4,7-bis-(4′-trifluoromethyl-biphenyl-4-yl)-1,10-phenanthroline.

Cu(I)-catalyzed oxidative cyclization of alkynyl oxiranes and oxetanes

In the presence of a Cu(I) catalyst and a pyridine oxide, alkynyl oxiranes and oxetanes can be converted into functionalized five- or six-membered α,β-unsaturated lactones or dihydrofuranaldehydes. This new oxidative cyclization is proposed to proceed via an unusual allenyloxypyridinium intermediate.

Preparation, physical properties and n-type FET characteristics of substituted diindenopyrazinediones and bis(dicyanomethylene) derivatives

A series of halogen and alkyl substituted diindenopyrazinediones and bis(dicyanomethylene) derivatives have been synthesized as new n-type organic semiconductors based on nitrogen-containing heterocycles. Halogen groups were introduced to improve the electron injection. Their crystal structures and solid physical properties are discussed. Alkyl groups were introduced to increase the solubility in organic solvents. Furthermore, hexanoyl groups were introduced by oxidation of alkyl groups to increase the solubility and electron affinity. Dicyanomethylene groups were also introduced to further enhance the electron-accepting properties. Drop-cast as well as vapour deposited thin films showed n-type FET properties.

PROTEIN CROSSLINKING INHIBITOR AND USE OF THE SAME

The present invention relates to: a ketone compound having transglutaminase-inhibiting activity, which is represented by the following Formula 1, 2, or 3: wherein R1 is a substituted or unsubstituted aryl or heterocyclyl group, R2, R3, and R4 are hydrogen atoms, n is 2, X is halogen, R5 and R6 independently represent a hydrogen atom or a substituted or unsubstituted C1-C10 alkyl, aryl, or aralkyl group, wherein R5 and R6 are not hydrogen atoms at the same time, or R5 and R6 may be taken together to form a saturated or unsaturated and substituted or unsubstituted heterocyclyl group containing a nitrogen atom (N); an inhibitor of protein crosslinking comprising the compound; and a composition for preventing or treating a protein-crosslinking causative disease, which comprises the compound or the protein crosslinking inhibitor.

Synthesis of enantiomerically pure γ-azidoalcohols by lipase-catalyzed transesterification

An enantioselective synthesis of chiral γ-azidoalcohols via lipase-catalyzed resolution is described. The efficiency of various lipases and the effect of different solvents have been studied. Pseudomonas cepacia immobilized on diatomaceous earth (PS-D) in n-hexane catalyzed the transesterification process in an efficient manner providing γ-azidoalcohols in high enantiomeric excess.