318515-74-1

Basic information

• Product Name: 3-phenylcyclobutan-1-one O-benzoyl oxime
• Synonyms: 3-phenylcyclobutan-1-one O-benzoyl oxime
• CAS NO: 318515-74-1
• Molecular Weight: 265.312
• Mol File: 318515-74-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 3-phenylcyclobutan-1-one O-benzoyl oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenylcyclobutan-1-one O-benzoyl oxime(318515-74-1)
• EPA Substance Registry System: 3-phenylcyclobutan-1-one O-benzoyl oxime(318515-74-1)

Safety Data

• Hazardous Substances Data: 318515-74-1(Hazardous Substances Data)

Upstream product

• 99059-91-3 3-phenylcyclobutan-1-one oxime 
• 98-88-4 benzoyl chloride 
• 100-42-5 styrene 
• 13866-28-9 2,2-dichloro-3-phenylcyclobutanone 

Downstream Products

• 20132-76-7 3-phenyl-butyronitrile 
• 1447034-71-0 4-(diphenylamino)-3-phenylbutanenitrile 
• 108716-86-5 formic acid 2-phenyl-3-quinolin-2-yl-propyl ester 
• 14908-85-1 3-Phenyl-buten-⁽³⁾-saeurenitril 

Relevant articles and documents

Copper-Catalyzed Sulfonylation of Cyclobutanone Oxime Esters with Sulfonyl Hydrazides

A copper-catalyzed radical cross-coupling of cyclobutanone oxime esters with sulfonyl hydrazides has been developed. The copper-based catalytic system proved crucial for cleavage of the C-C bond of cyclobutanone oximes and for selective C-S bond-formation involving persistent sulfonyl-metal radical intermediates. This protocol is distinguished by the low-cost catalytic system, which does not require ligand, base, or toxic cyanide salt, and by the use of readily accessible starting materials, as well as broad substrate scope, providing an efficient approach to various diversely substituted cyano-containing sulfones.

Synthesis of trisubstituted alkenes by Ni-catalyzed hydroalkylation of internal alkynes with cycloketone oxime esters

A method for Ni-catalyzed hydroalkylation of internal alkynes with cycloketone oxime esters was developed. The reaction has a broad substrate scope. This hydroalkylation shows excellent regio-and stereo-selectivity. This method enables readily available starting materials to be used to access a range of cyano-substituted single-configuration trisubstituted alkenes. These are valuable feedstock chemicals and are widely used in synthetic and medicinal chemistry.

Copper-catalyzed tandem aerobic oxidative cyclization for the synthesis of 4-cyanoalkylpyrrolo[1,2-a]quinoxalines from 1-(2-aminophenyl)pyrroles and cyclobutanone oxime esters

A copper-catalyzed tandem ring-opening/cyclization reaction for the synthesis of 4-cyanoalkylpyrrolo[1,2-a]quinoxalines from 1-(2-aminophenyl)pyrroles and cyclobutanone oxime esters has been developed. This reaction involves C-C bond cleavage and C-C and C-N bond constructions with good functional group tolerance. A wide range of products are obtained in moderate to good yields under mild conditions.