31913-88-9Relevant academic research and scientific papers
Amino-sulfonation of alkenes in a three-component reaction
Cordero, Franca M.,Cacciarini, Martina,Machetti, Fabrizio,De Sarlo, Francesco
, p. 1407 - 1411 (2002)
2-Aminoalkanesulfonic acids have been synthesized by a three-component alkene/SO3·-DMF/acetonitrile reaction, followed by hydrolysis. Trifluoromethanesulfonic acid was added to the amino-sulfonation mixture to accelerate the reaction and prevent the competitive formation of by-products. The reported two-step procedure provided a concise and versatile approach to new analogues of the natural amino acid taurine. Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002.
