319429-11-3Relevant academic research and scientific papers
Copper-catalyzed dehydrogenative reaction: Synthesis of amide from aldehydes and aminopyridine
Yang, Sizhuo,Yan, Hao,Ren, Xiaoyu,Shi, Xiaokang,Li, Jian,Wang, Yuling,Huang, Guosheng
, p. 6431 - 6435 (2013)
We have developed a highly efficient method in the presence of copper catalyst to form amides from aminopyridines and aldehydes. This method is simple, environmental benign and has practical advantages in the amide synthesis.
Cu-catalyzed cross-coupling of methyl ketones and pyridin-2-amines for the synthesis of N-(2-pyridyl)-α-ketoamides
Chen, Ali,Guo, Pengfeng,Lin, Haoming,Liu, Xiang,Rao, Chuixiong,Yang, Daji,Yu, Yue
, p. 417 - 421 (2020/11/30)
An efficient copper-catalyzed strategy for the synthesis of α-ketoamides via cross-coupling of methyl ketones and pyridin-2-amines is described. This transformation has provided a simple process for the formation of C?N and C=O bonds to prepare α-ketoamid
Transformation of aldehydes or alcohols to amides at room temperature under aqueous conditions
Dong, Dao-Qing,Hao, Shuang-Hong,Zhang, Hui,Wang, Zu-Li
, p. 1597 - 1599 (2017/07/17)
A novel and efficient method for the synthesis of amide has been developed. The reactions proceeded smoothly under aqueous conditions at room temperature and generated the corresponding products in good to excellent yields. It is worth noting that alkyl amines which did not react in known approaches are well tolerated in our system.
