319451-89-3

Upstream product

• 319451-88-2 tert-butyl 4-[4-nitro-3-(trimethylsilylmethyl)phenoxy]piperidine-1-carboxylate 
• 179756-49-1 7-formyl-2-naphthalene-carbonitrile 
• 350-46-9 4-Fluoronitrobenzene 
• 138227-62-0 tert-butyl 4-(4-nitrophenoxy)piperidine-1-carboxylate 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 

Downstream Products

• 319451-91-7 4-{4-benzyloxycarbonylamino-3-[2-(7-cyano-naphthalen-2-yl)-2-hydroxy-ethyl]-phenoxy}-piperidine-1-carboxylic acid tert-butyl ester 
• 319451-92-8 1-(benzyloxycarbonyl)-5-[1-(t-butoxycarbonyl)piperidin-4-yloxy]-2-(7-cyanonaphthalen-2-yl)indoline 
• 319451-90-6 4-{4-amino-3-[2-(7-cyano-naphthalen-2-yl)-2-hydroxy-ethyl]-phenoxy}-piperidine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Indoline derivatives I: Synthesis and Factor Xa (FXa) inhibitory activities

A series of bisamidine derivatives each having a ring structure in the center of the molecule was synthesized and their Factor Xa (FXa) inhibitory activities were evaluated. Among them, some indoline derivatives showed potent inhibitory activities in vitr