320349-99-3Relevant academic research and scientific papers
Design and development of 2,3-benzodiazepine (CFM) noncompetitive AMPA receptor antagonists
Gitto, Rosaria,Zappala, Maria,De Sarro, Giovambattista,Chimirri, Alba
, p. 129 - 134 (2007/10/03)
2,3-Benzodiazepines represent a class of heterocyclic compounds that interact with AMPA-type glutamate receptors in a noncompetitive manner. These compounds have attracted great interest for their pharmacological effects against acute and chronic neurodeg
Solid-phase Friedel-Crafts acylation on polystyrene resins-synthesis of antiepiletic 1-aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones
Bevacqua, Francesca,Basso, Andrea,Gitto, Rosaria,Bradley, Mark,Chimirri, Alba
, p. 7683 - 7685 (2007/10/03)
Friedel-Crafts acylation with various acyl chlorides of resin-bound 3,4-dimethoxyphenylacetate afforded resin bound ketones which, following treatment with hydrazine, were converted into the corresponding 2,3-benzodiazepines in good yields and purities.
