320600-36-0Relevant academic research and scientific papers
Enantiomerical excess determination, purification and biological evaluation of (3S) and (3R) α,β-butenolide analogues of isobenzofuranone
Lipka, Emmanuelle,Vaccher, Marie-Pierre,Vaccher, Claude,Len, Christophe
, p. 501 - 504 (2007/10/03)
The asymmetric synthesis of isobenzofurane analogues, new potential antiviral agents, is reported. High performance liquid chromatography (HPLC) was the technique chosen to separate the enantiomers. We describe this chiral separation and then determine th
Stereoisomeric pyrimidine nucleoside analogues based on the 1,3-dihydrobenzo[c]furan core
Ewing, David F.,Fahmi, Nour-Eddine,Len, Christophe,Mackenzie, Grahame,Pranzo, Alessandra
, p. 3561 - 3565 (2007/10/03)
Stereoisomeric pyrimidine nucleoside analogues based on the 1,3-dihydrobenzo[c]furan core was described. The overall yield of 3-benzoyloxymethyl-1,3-dihydro-1-methoxybenzo[c]furan from aldehyde was 42%. After removal of the protecting group the four stere
Simple and stereoselective syntheses of nucleoside analogues with a benzo[c]furan glycone moiety
Ewing, David F.,Fahmi, NourEddine,Mackenzie, Grahame,Pranzo, Alessandra
, p. 559 - 563 (2007/10/03)
A series of d4T analogues have been synthesised in which the 2',3'- didehydro-2',3'-dideoxyribose moiety is replaced by a benzo[c]furan core. A simple strategy has been developed to access a range of compounds for biological screening. In addition, a ster
