321125-08-0

Basic information

• Product Name: 2-O-(4-methoxybenzoyl)-3,4-di-O-triethylsilyl-β-D-xylopyranosyl-(1→3)-2-O-acetyl-4-O-triethylsilyl-α,β-L-arabinopyranosyl trichloroacetimidate
• Synonyms: 2-O-(4-methoxybenzoyl)-3,4-di-O-triethylsilyl-β-D-xylopyranosyl-(1→3)-2-O-acetyl-4-O-triethylsilyl-α,β-L-arabinopyranosyl trichloroacetimidate
• CAS NO: 321125-08-0
• Molecular Weight: 945.595
• Mol File: 321125-08-0.mol

Chemical Properties

• CAS DataBase Reference: 2-O-(4-methoxybenzoyl)-3,4-di-O-triethylsilyl-β-D-xylopyranosyl-(1→3)-2-O-acetyl-4-O-triethylsilyl-α,β-L-arabinopyranosyl trichloroacetimidate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-O-(4-methoxybenzoyl)-3,4-di-O-triethylsilyl-β-D-xylopyranosyl-(1→3)-2-O-acetyl-4-O-triethylsilyl-α,β-L-arabinopyranosyl trichloroacetimidate(321125-08-0)
• EPA Substance Registry System: 2-O-(4-methoxybenzoyl)-3,4-di-O-triethylsilyl-β-D-xylopyranosyl-(1→3)-2-O-acetyl-4-O-triethylsilyl-α,β-L-arabinopyranosyl trichloroacetimidate(321125-08-0)

Safety Data

• Hazardous Substances Data: 321125-08-0(Hazardous Substances Data)

Upstream product

• 545-06-2 trichloroacetonitrile 
• 87-72-9 D-Xylose 
• 70798-31-1 benzyl 2-O-acetyl-β-L-arabinopyranoside 
• 219906-50-0 4-Methoxy-benzoic acid (2S,3R,4R,5R)-2-benzyloxy-4,5-bis-triethylsilanyloxy-tetrahydro-pyran-3-yl ester 
• 321125-07-9 2-O-(4-methoxybenzoyl)-3,4-di-O-triethylsilyl-α,β-D-xylopyranosyl trichloroacetimidate 
• 994-30-9 triethylsilyl chloride 
• 493012-06-9 allyl 2-O-acetyl-β-L-arabinopyranoside 
• 6763-34-4 D-xylose 
• 1233-03-0 1,2,3,4-tetra-O-acetyl-L-arabinopyranose 
• 1253283-82-7 4-methylphenyl 3,4-O-(1-methylethylidene)-1-thio-α-L-arabinopyranoside 
• 1253283-83-8 p-methylphenyl 2-O-acetyl-1-thio-α-L-arabinopyranoside 
• 18403-22-0 (3aS,6S,7R,7aR)-6-Benzyloxy-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-7-ol 
• 7473-38-3 benzyl β-L-arabinopyranoside 
• 18403-12-8 benzyl β-D-xylopyranoside 

Downstream Products

• 219906-58-8 C₇₃H₁₂₈O₁₆Si₄ 
• 321125-18-2 diosgenin-3-yl 2-O-(4-methoxybenzoyl)-3,4-di-O-triethylsilyl-β-D-xylopyranosyl-(1->3)-2-O-acetyl-4-O-triethylsilyl-α-L-arabinopyranoside 
• 374617-90-0 C₆₄H₁₀₆O₁₇Si₃ 
• 714264-94-5 C₇₁H₁₂₆O₁₄Si₄ 
• 714264-96-7 C₇₇H₁₄₀O₁₅Si₅ 
• 478286-99-6 C₆₆H₁₁₂O₁₅Si₃ 

Relevant articles and documents

Synthesis, conformational analysis and SAR research of OSW-1 analogues

A series of novel OSW-1 analogues were synthesized by coupling disaccharides (2-O-4-methoxylbenzoyl-β-D-xylopyranosyl-(1→3)-2-O-acetyl-α-L-arabinopyranosyl) or (2-O-4-(E)-cinnamoyl-β-D-xylopyranosyl-(1→3)-2-O-acetyl-α-L-arabinopyranosyl) and their 1→4 lin

Study on the synthesis of regio- and stereoisomers of the disaccharide unit of the OSW-1 saponin

A convenient method for the preparation of the OSW-1 disaccharide unit was developed and used for the synthesis of its regio- and stereoisomers. The corresponding allyl and 1-propenyl xylopyranosides and arabinopyranosides were used as starting materials.

First total synthesis of an exceptionally potent antitumor saponin, OSW- 1

OSW-1 (1), an acylated disaccharide cholestane saponin from Ornithogalum saudersiae with exceptionally potent antitumor activity, was first synthesized from commercially available dehydroisoandrosterone, L-arabinose, and D-xylose in total 27 steps with the longest linear sequence of 14 steps and in 6% yield.