32121-60-1

Upstream product

• 1499-00-9 2-phenylaziridine 
• 108-98-5 thiophenol 
• 37167-62-7 bromo-phenyl-acetic acid methyl ester 
• 51256-38-3 methyl α-phenyl-α-(phenylthio)acetate 
• 930-69-8 sodium thiophenolate 

Downstream Products

• 153576-76-2 N-(2-phenylthio-2-phenylethyl)-3,4-dimethoxyphenylacetamide 
• 153576-70-6 N-(2-phenylthio-2-phenylethyl)-3,4-dimethoxybenzamide 

Relevant academic research and scientific papers

Synthesis of mexiletine analogues from non-activated aziridines

A general method for the synthesis of mexiletine analogues by nucleophilic ring opening of non-activated racemic aziridines has been developed (Scheme 1). Structural variation is introduced by employing different nucleophiles or by altering the substitution on the aziridine ring.