321658-65-5Relevant academic research and scientific papers
Pd-Catalyzed Asymmetric C-H Bond Activation for the Synthesis of P-Stereogenic Dibenzophospholes
Li, Zhen,Lin, Zi-Qi,Yan, Chao-Guo,Duan, Wei-Liang
supporting information, p. 3916 - 3920 (2019/11/14)
Pd-catalyzed asymmetric C-H bond activation for the synthesis of P-stereogenic dibenzophospholes was efficiently achieved via two types of catalytic systems. Chiral phosphoric amides/acids as ligands provided the products with up to 5:95 er, and (R)-segph
Ruthenium-Catalyzed Gram-Scale Preferential C-H Arylation of Tertiary Phosphine
Li, Jia-Wei,Wang, Liang-Neng,Li, Ming,Tang, Pan-Ting,Luo, Xiao-Peng,Kurmoo, Mohamedally,Liu, Yue-Jin,Zeng, Ming-Hua
supporting information, p. 2885 - 2889 (2019/04/30)
A general protocol for site-preferential mono-C-H arylation of tertiary phosphine ligands catalyzed by a ruthenium(II) complex was devised. This protocol gives access to a series of modified Buchwald-biaryl monophosphines on a gram scale in moderate to excellent yields. A catalytic cycle is proposed derived from knowledge of the intermediates observed by ESI-MS. Importantly, these monoarylated products could be further transformed into dibenzophosphole derivatives.
