321980-95-4

Basic information

• Product Name: Benzaldehyde, 4-bromo-, [4-(4-methylphenyl)-2-thiazolyl]hydrazone
• CAS NO: 321980-95-4
• Molecular Formula: C17H14BrN3S
• Molecular Weight: 372.288
• Mol File: 321980-95-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 4-bromo-, [4-(4-methylphenyl)-2-thiazolyl]hydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 4-bromo-, [4-(4-methylphenyl)-2-thiazolyl]hydrazone(321980-95-4)
• EPA Substance Registry System: Benzaldehyde, 4-bromo-, [4-(4-methylphenyl)-2-thiazolyl]hydrazone(321980-95-4)

Safety Data

• Hazardous Substances Data: 321980-95-4(Hazardous Substances Data)

Upstream product

• 1629144-33-7 2-phenoxy-4-(p-tolyl)thiazole 
• 4872-78-0 2-hydrazino-4-(4'-tolyl)thiazole 
• 1122-91-4 4-bromo-benzaldehyde 

Relevant articles and documents

2,4- and 2,5-disubstituted arylthiazoles: Rapid synthesis by C-H coupling and biological evaluation

Life-threatening infections caused by bacteria that have developed resistance to common antibiotics, such as methicillin-resistant Staphylococcus aureus (MRSA), have become a serious problem in hospitals and other areas all over the world. Thus, the development of an effective class of antibiotics against these bacteria is an urgent subject. Herein, we report a step-economical and diversity-oriented synthesis of a series of 2-arylidenehydrazinyl-4- arylthiazole and 2-arylidenehydrazinyl-5-arylthiazole analogues that utilizes C-H coupling methodologies. A library of 54 new congeners were synthesized and tested for their biological potential. Moreover, new knowledge regarding the structure-activity relationships (SARs) of these heterobiaryl compounds was collected. Copyright