1629144-33-7

Basic information

• Product Name: 2-phenoxy-4-(p-tolyl)thiazole
• CAS NO: 1629144-33-7
• Molecular Weight: 267.351
• Mol File: 1629144-33-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-phenoxy-4-(p-tolyl)thiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenoxy-4-(p-tolyl)thiazole(1629144-33-7)
• EPA Substance Registry System: 2-phenoxy-4-(p-tolyl)thiazole(1629144-33-7)

Safety Data

• Hazardous Substances Data: 1629144-33-7(Hazardous Substances Data)

Upstream product

• 108-95-2 phenol 
• 5720-05-8 4-methylphenylboronic acid 
• 73120-22-6 2-phenoxythiazole 

Downstream Products

• 4872-78-0 2-hydrazino-4-(4'-tolyl)thiazole 
• 321980-95-4 2-(2-(4-bromobenzylidene)hydrazinyl)-4-(4-methylphenyl)thiazole 
• 78559-90-7 2-(2-(4-methoxybenzylidene)hydrazinyl)-4-(4-methylphenyl)thiazole 

Relevant articles and documents

2,4- and 2,5-disubstituted arylthiazoles: Rapid synthesis by C-H coupling and biological evaluation

Life-threatening infections caused by bacteria that have developed resistance to common antibiotics, such as methicillin-resistant Staphylococcus aureus (MRSA), have become a serious problem in hospitals and other areas all over the world. Thus, the development of an effective class of antibiotics against these bacteria is an urgent subject. Herein, we report a step-economical and diversity-oriented synthesis of a series of 2-arylidenehydrazinyl-4- arylthiazole and 2-arylidenehydrazinyl-5-arylthiazole analogues that utilizes C-H coupling methodologies. A library of 54 new congeners were synthesized and tested for their biological potential. Moreover, new knowledge regarding the structure-activity relationships (SARs) of these heterobiaryl compounds was collected. Copyright